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Query: SLC9A3R1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SLC9A3R1 0 -2.413 0.240 -0.810

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SLC9A3R1 Phosphorylation S280 -0.611 -0.277 _EALAEAALES(ph)PRPALVR_
SLC9A3R1 Phosphorylation S290 -0.404 -0.401 _SAS(ph)SDTSEELNSQDSPPK_
SLC9A3R1 Ubiquitylation K50 -1.732 _LVEPGSPAEK(gl)AGLLAGDR_
SLC9A3R1 Ubiquitylation K101 -2.049 _LLVVDPETDEQLQK(gl)LGVQVR_

Background Information for SLC9A3R1:





Protein-protein Interactions for SLC9A3R1

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDCA5 Cat. description Hein, Mann, Cell 2015
Category members IP bait SNRNP27 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SLC9A3R1

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PDZ IPR001478 0.15


Protein complexes (CORUM database) featuring SLC9A3R1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 681 (C-CFTR)2-NHERF-ezrin complex Database 0
Category members Corum 682 C-CFTR-NHERF(PDZ1 domain)-ezrin complex Database 0
Category members Corum 683 C-CFTR-NHERF(PDZ2 domain)-ezrin complex Database 0
Category members Corum 687 CFTR-NHERF-beta(2)AR signaling complex Database 0


Categories featuring SLC9A3R1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0015629 actin cytoskeleton Database 2.22
Category members GO Category GO:0019904 protein domain specific binding Database 1.85
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_561 PID_PDGFRB_PATHWAY 0 1.18
Category members GO Category GO:0030036 actin cytoskeleton organization Database 1.08
Category members GO Category GO:0030336 negative regulation of cell migration Database 0.85
Category members GO Category GO:0032947 protein complex scaffold Database 0.82
Category members GO Category GO:0005813 centrosome Database 0.75
Category members GO Category GO:0006461 protein complex assembly Database 0.57
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0032403 protein complex binding Database 0.49
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0008013 beta-catenin binding Database 0.35
Category members GO Category GO:0001726 ruffle Database 0.33
Category members GO Category GO:0030165 PDZ domain binding Database 0.29
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members GO Category GO:0030033 microvillus assembly Database 0.23
Category members GO Category GO:0032416 negative regulation of sodium:hydrogen antiporter activity Database 0.18
Category members GO Category GO:0019902 phosphatase binding Database 0.16
Category members GO Category GO:0005902 microvillus Database 0.13
Category members GO Category GO:0045121 membrane raft Database 0.11
Category members GO Category GO:0016055 Wnt signaling pathway Database 0.11
Category members GO Category GO:0070373 negative regulation of ERK1 and ERK2 cascade Database 0.1
Category members GO Category GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway Database 0.08
Category members GO Category GO:0043621 protein self-association Database 0.07
Category members GO Category GO:0030175 filopodium Database 0.05
Category members GO Category GO:0034613 cellular protein localization Database 0.04
Category members GO Category GO:0010766 negative regulation of sodium ion transport Database 0.04
Category members GO Category GO:0034635 glutathione transport Database 0.04
Category members GO Category GO:0070851 growth factor receptor binding Database 0.04
Category members GO Category GO:0045859 regulation of protein kinase activity Database 0.01
Category members Pathway Pathway_245 BIOCARTA_CFTR_PATHWAY 0 0
Category members Pathway Pathway_290 WNT_SIGNALING 0 0
Category members Pathway Pathway_430 PID_TXA2PATHWAY 0 0
Category members Disease phenotype Dominant_hypophosphatemia_with_nephrolithiasis_or_osteoporosis Dominant hypophosphatemia with nephrolithiasis or osteoporosis Database 0
Category members GO Category GO:0005102 receptor binding Database 0
Category members GO Category GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway Database 0
Category members GO Category GO:0012505 endomembrane system Database 0
Category members GO Category GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling Database 0
Category members GO Category GO:0016324 apical plasma membrane Database 0
Category members GO Category GO:0017081 chloride channel regulator activity Database 0
Category members GO Category GO:0019933 cAMP-mediated signaling Database 0
Category members GO Category GO:0030643 cellular phosphate ion homeostasis Database 0
Category members GO Category GO:0031526 brush border membrane Database 0
Category members GO Category GO:0031528 microvillus membrane Database 0
Category members GO Category GO:0031698 beta-2 adrenergic receptor binding Database 0
Category members GO Category GO:0045177 apical part of cell Database 0
Category members GO Category GO:0051898 negative regulation of protein kinase B signaling Database 0
Category members GO Category GO:0060158 phospholipase C-activating dopamine receptor signaling pathway Database 0
Category members GO Category GO:0070293 renal absorption Database 0


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