Results for the Category
adenylate cyclase-activating dopamine receptor signaling pathway
(GO:0007191)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| GNB1 | 0 | -0.700 | 0.650 | 0.713 | 0.504 | 0.538 | ||
| GNB3 | 0 | -1.020 | 1.280 | 0.713 | 0.504 | 0.538 | ||
| GNAS | 0 | 0.840 | -0.750 | |||||
| GNAS | 0 | 0.840 | -0.750 | |||||
| GNAS | 0 | 0.840 | -0.750 | -0.166 | -0.094 | 0.032 | 0.420 | 0.504 |
| SLC9A3R1 | 0 | 0.240 | -0.810 | |||||
| GNAL | 0 | 1.660 | -1.170 | |||||
| GNAL | 0 | 1.660 | -1.170 | -0.166 | -0.094 | 0.032 | 0.420 | 0.504 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| GNAL | Ubiquitylation | K58 | -1.182 | 0.161 | _STIVK(gl)QM(ox)R_ |
| GNAS | Ubiquitylation | K8 | 0.430 | 0.328 | _GCLGNSK(gl)TEDQRNEEK(gl)AQR_ |
| GNAS | Ubiquitylation | K17 | -0.011 | _GCLGNSK(gl)TEDQRNEEK(gl)AQR_ | |
| GNAS | Ubiquitylation | K32 | 0.249 | -0.446 | _QLQK(gl)DKQVYR_ |
| GNAS | Ubiquitylation | K58 | -1.182 | 0.161 | _STIVK(gl)QM(ox)R_ |
| GNAS | Ubiquitylation | K92 | -1.333 | -0.290 | _ATK(gl)VQDIKNNLK_ |
| GNAS | Ubiquitylation | K97 | 0.076 | _VQDIK(gl)NNLK_ | |
| GNAS | Ubiquitylation | K167 | -1.721 | _LHALK(gl)LR_ | |
| GNAS | Ubiquitylation | K301 | -0.955 | -0.198 | _QDLLAEK(gl)VLAGK_ |
| GNAS | Ubiquitylation | K308 | -0.472 | _SK(gl)IEDYFPEFAR_ | |
| GNB1 | Ubiquitylation | K23 | -0.282 | _K(gl)ACADATLSQITNNIDPVGR_ | |
| GNB1 | Ubiquitylation | K209 | -0.296 | -0.249 | _LFVSGACDASAK(gl)LWDVR_ |
| GNB3 | Ubiquitylation | K23 | -0.282 | _K(gl)ACADATLSQITNNIDPVGR_ | |
| GNB3 | Ubiquitylation | K209 | -0.296 | -0.249 | _LFVSGACDASAK(gl)LWDVR_ |
| SLC9A3R1 | Ubiquitylation | K50 | -1.732 | _LVEPGSPAEK(gl)AGLLAGDR_ | |
| SLC9A3R1 | Ubiquitylation | K101 | -2.049 | _LLVVDPETDEQLQK(gl)LGVQVR_ | |
| SLC9A3R1 | Phosphorylation | S280 | -0.611 | -0.277 | _EALAEAALES(ph)PRPALVR_ |
| SLC9A3R1 | Phosphorylation | S290 | -0.404 | -0.401 | _SAS(ph)SDTSEELNSQDSPPK_ |
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