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Query: RAB11A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RAB11A 0 2.193 1.130 -0.130
RAB11A 0 2.193 1.130 -0.130 0.324 0.697 0.458

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RAB11A Ubiquitylation K224 -0.187 0.901 _IVSQK(gl)QMSDRR_
RAB11A Ubiquitylation K69 -0.533 0.554 _VVLIGDSGVGK(gl)SNLLSR_
RAB11A Ubiquitylation K106 0.335 _SIQVDGKTIK(gl)_
RAB11A Ubiquitylation K103 -0.360 -0.185 _SIQVDGK(gl)TIK_

Background Information for RAB11A:


Pubmed-RAB11A »
Uniprot-RAB11A »
Biogrid-RAB11A »
ProteomicsDB-RAB11A »

Tumorportal-RAB11A »
COSMIC-RAB11A »
GenomeRNAi-RAB11A »
Genecards-RAB11A


Protein-protein Interactions for RAB11A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait RAB11A Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB11A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RAB11A
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members EF_GTP-bd_dom IPR000795 1.57
Category members Ran_GTPase IPR002041 1.25
Category members Small_GTPase_ARF/SAR IPR006689 0.8
Category members Small_GTPase_Ras IPR020849 0.7
Category members Small_GTPase_Rho IPR003578 0.65
Category members Small_GTPase IPR001806 0.65
Category members Small_GTPase_Rab_type IPR003579 0.51
Category members MIRO-like IPR013684 0.4
Category members Small_GTP-bd_dom IPR005225 0.32


Protein complexes (CORUM database) featuring RAB11A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3941 RCP-Rab11 complex Database 0.18


Categories featuring RAB11A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0006913 nucleocytoplasmic transport Database 2.96
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members GO Category GO:0032154 cleavage furrow Database 2.01
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_666 KEGG_ENDOCYTOSIS 0 1.25
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0016192 vesicle-mediated transport Database 1.1
Category members Pathway Pathway_662 PID_IL8_CXCR2_PATHWAY 0 0.62
Category members GO Category GO:0030659 cytoplasmic vesicle membrane Database 0.62
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0030670 phagocytic vesicle membrane Database 0.37
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0005622 intracellular Database 0.32
Category members Pathway Pathway_849 PID_NOTCH_PATHWAY 0 0.29
Category members GO Category GO:0006184 GTP catabolic process Database 0.29
Category members GO Category GO:0055037 recycling endosome Database 0.29
Category members GO Category GO:0030424 axon Database 0.23
Category members Pathway Pathway_1273 BIOCARTA_RAB_PATHWAY 0 0.18
Category members GO Category GO:0051223 regulation of protein transport Database 0.18
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members GO Category GO:0045335 phagocytic vesicle Database 0.16
Category members GO Category GO:0000910 cytokinesis Database 0.15
Category members GO Category GO:0005802 trans-Golgi network Database 0.13
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members GO Category GO:0031175 neuron projection development Database 0.12
Category members Pathway Pathway_99 REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 0 0.08
Category members Pathway Pathway_296 PID_ARF6_DOWNSTREAM_PATHWAY 0 0.08
Category members GO Category GO:0019905 syntaxin binding Database 0.05
Category members Pathway Pathway_242 REACTOME_AQUAPORIN_MEDIATED_TRANSPORT 0 0
Category members Pathway Pathway_248 REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS 0 0
Category members Pathway Pathway_266 KEGG_VASOPRESSIN_REGULATED_WATER_REABSORPTION 0 0
Category members Pathway Pathway_430 PID_TXA2PATHWAY 0 0
Category members GO Category GO:0006833 water transport Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0030133 transport vesicle Database 0
Category members GO Category GO:0032402 melanosome transport Database 0
Category members GO Category GO:0045773 positive regulation of axon extension Database 0
Category members GO Category GO:0048169 regulation of long-term neuronal synaptic plasticity Database 0
Category members GO Category GO:0048227 plasma membrane to endosome transport Database 0
Category members GO Category GO:0055038 recycling endosome membrane Database 0


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