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Query: PPT1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PPT1 0 1.077 1.320 -0.730

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PPT1 Ubiquitylation K224 1.077 _NLMALKK(gl)_
PPT1 Ubiquitylation K253 0.222 _SGQAK(gl)ETIPLQETSLYTQDR_
PPT1 Ubiquitylation K174 -0.445 _TLNAGAYSK(gl)VVQER_

Background Information for PPT1:


Pubmed-PPT1 »
Uniprot-PPT1 »
Biogrid-PPT1 »
ProteomicsDB-PPT1 »

Tumorportal-PPT1 »
COSMIC-PPT1 »
GenomeRNAi-PPT1 »
Genecards-PPT1


Protein-protein Interactions for PPT1
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in PPT1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Palm_thioest IPR002472 0.17
Category members AB_hydrolase IPR029058 0


Protein complexes (CORUM database) featuring PPT1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PPT1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005576 extracellular region Database 10.9
Category members GO Category GO:0005615 extracellular space Database 4.72
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0043524 negative regulation of neuron apoptotic process Database 0.66
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0030163 protein catabolic process Database 0.38
Category members GO Category GO:0030149 sphingolipid catabolic process Database 0.32
Category members GO Category GO:0008021 synaptic vesicle Database 0.28
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0030425 dendrite Database 0.26
Category members GO Category GO:0006309 apoptotic DNA fragmentation Database 0.26
Category members GO Category GO:0030424 axon Database 0.23
Category members GO Category GO:0007042 lysosomal lumen acidification Database 0.18
Category members GO Category GO:0030308 negative regulation of cell growth Database 0.18
Category members GO Category GO:0032429 regulation of phospholipase A2 activity Database 0.17
Category members GO Category GO:0048549 positive regulation of pinocytosis Database 0.17
Category members GO Category GO:0031579 membrane raft organization Database 0.17
Category members GO Category GO:0045121 membrane raft Database 0.11
Category members GO Category GO:0006907 pinocytosis Database 0.11
Category members GO Category GO:0043005 neuron projection Database 0.08
Category members GO Category GO:0045202 synapse Database 0.06
Category members Pathway Pathway_74 KEGG_LYSOSOME 0 0
Category members GO Category GO:0002084 protein depalmitoylation Database 0
Category members GO Category GO:0005764 lysosome Database 0
Category members GO Category GO:0006464 cellular protein modification process Database 0
Category members GO Category GO:0006898 receptor-mediated endocytosis Database 0
Category members GO Category GO:0007040 lysosome organization Database 0
Category members GO Category GO:0007269 neurotransmitter secretion Database 0
Category members GO Category GO:0007399 nervous system development Database 0
Category members GO Category GO:0007420 brain development Database 0
Category members GO Category GO:0007601 visual perception Database 0
Category members GO Category GO:0007625 grooming behavior Database 0
Category members GO Category GO:0008306 associative learning Database 0
Category members GO Category GO:0008344 adult locomotory behavior Database 0
Category members GO Category GO:0008474 palmitoyl-(protein) hydrolase activity Database 0
Category members GO Category GO:0016042 lipid catabolic process Database 0
Category members GO Category GO:0016290 palmitoyl-CoA hydrolase activity Database 0
Category members GO Category GO:0043025 neuronal cell body Database 0
Category members GO Category GO:0044257 cellular protein catabolic process Database 0
Category members GO Category GO:0044265 cellular macromolecule catabolic process Database 0
Category members GO Category GO:0048260 positive regulation of receptor-mediated endocytosis Database 0
Category members GO Category GO:0048666 neuron development Database 0
Category members GO Category GO:0050803 regulation of synapse structure and activity Database 0


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