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Query: NBR1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NBR1 0 -3.558 0.470 -0.040 -2.408

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NBR1 Ubiquitylation K539 -0.515 -0.635 _QLGEVTEQTEGTAACIPQKAK(gl)_
NBR1 Ubiquitylation K627 -0.779 -1.425 _ALPDSMVSVK(gl)R_
NBR1 Ubiquitylation K464 -0.807 -2.087 _LSHK(gl)GQQFGPR_
NBR1 Ubiquitylation K515 -0.852 _TDDLTCQQEETFLLAK(gl)EER_
NBR1 Ubiquitylation K767 -1.436 _GAEGK(gl)PGVEAGQEPAEAGER_

Background Information for NBR1:


Pubmed-NBR1 »
Uniprot-NBR1 »
Biogrid-NBR1 »
ProteomicsDB-NBR1 »

Tumorportal-NBR1 »
COSMIC-NBR1 »
GenomeRNAi-NBR1 »
Genecards-NBR1


Protein-protein Interactions for NBR1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GTSE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CORO6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait JUNB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LTBR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYPD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL41 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCGN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPPL2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VAPB Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NBR1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members UBA-like IPR009060 0.17
Category members UBA/transl_elong_EF1B_N_euk IPR015940 0.04
Category members Znf_ZZ IPR000433 0.01
Category members OPR_PB1 IPR000270 0


Protein complexes (CORUM database) featuring NBR1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring NBR1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0043130 ubiquitin binding Database 1.22
Category members GO Category GO:0045668 negative regulation of osteoblast differentiation Database 0.29
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0051019 mitogen-activated protein kinase binding Database 0.13
Category members GO Category GO:0032872 regulation of stress-activated MAPK cascade Database 0.11
Category members GO Category GO:0005770 late endosome Database 0.09
Category members GO Category GO:0000407 pre-autophagosomal structure Database 0
Category members GO Category GO:0005764 lysosome Database 0
Category members GO Category GO:0005776 autophagic vacuole Database 0
Category members GO Category GO:0016236 macroautophagy Database 0
Category members GO Category GO:0030500 regulation of bone mineralization Database 0
Category members GO Category GO:0031410 cytoplasmic vesicle Database 0
Category members GO Category GO:0031430 M band Database 0
Category members GO Category GO:0051259 protein oligomerization Database 0


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