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bioLOGIC Data

Query: MAGED1

RNAi screen result	RNAPII IP (PI)	CSB IP	CSB IP (PI)	Chrom.	Chrom. (PI)	Phosphorylation	Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
MAGED1	0	-3.552	-0.230	0.630	-1.300			-2.013	-0.274

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence
MAGED1	Ubiquitylation	K480	-1.406	-0.607	_LVK(gl)YLMLK_
MAGED1	Ubiquitylation	K522		-0.631	_ACFVLEK(gl)K_
MAGED1	Ubiquitylation	K644		-0.635	_SYHETSK(gl)MK_
MAGED1	Ubiquitylation	K189	-0.595	-0.649	_AWNDTTK(gl)APTADTQTQNVNQAK_
MAGED1	Ubiquitylation	K656	-1.786	-0.667	_FIAEVQK(gl)RDPR_
MAGED1	Ubiquitylation	K613		-0.842	_KLLTYEFVK(gl)QK_
MAGED1	Ubiquitylation	K489		-1.425	_DYTK(gl)VPIKR_
MAGED1	Ubiquitylation	K493		-1.472	_DYTKVPIK(gl)R_
MAGED1	Ubiquitylation	K147	-1.676		_SEMAFK(gl)AQNATTK_
MAGED1	Ubiquitylation	K251	-0.611		_K(gl)INNLNVEENSSGDQR_
MAGED1	Ubiquitylation	K605	-1.583		_K(gl)LLTYEFVK_
MAGED1	Ubiquitylation	K646	-1.548		_SYHETSKMK(gl)_

Background Information for MAGED1:

Pubmed-MAGED1 »

Uniprot-MAGED1 »

Biogrid-MAGED1 »

ProteomicsDB-MAGED1 »

Tumorportal-MAGED1 »

COSMIC-MAGED1 »

GenomeRNAi-MAGED1 »

Genecards-MAGED1

Protein-protein Interactions for MAGED1

Show screen data for	Category Name and Description	Link to cat description	Data Source

Protein Domains in MAGED1

	Domain name	Domain Description	TC-NER relevance -log10(p-value)

Protein complexes (CORUM database) featuring MAGED1

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)

Categories featuring MAGED1

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0005515	protein binding	Database	INF
Category members	GO Category	GO:0005737	cytoplasm	Database	12.81
Category members	GO Category	GO:0003713	transcription coactivator activity	Database	3.68
Category members	DDR Literature	pubmedid:19647519	Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation		3.6
Category members	GO Category	GO:0043234	protein complex	Database	2.73
Category members	Pathway	Pathway_837	REACTOME_APOPTOSIS	0	2.39
Category members	Pathway	Pathway_221	REACTOME_SIGNALLING_BY_NGF	0	2.14
Category members	GO Category	GO:0006915	apoptotic process	Database	2.12
Category members	GO Category	GO:0005886	plasma membrane	Database	1.21
Category members	GO Category	GO:0045892	negative regulation of transcription, DNA-dependent	Database	1.15
Category members	Pathway	Pathway_1016	REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS	0	0.87
Category members	GO Category	GO:0042981	regulation of apoptotic process	Database	0.79
Category members	Pathway	Pathway_529	KEGG_NEUROTROPHIN_SIGNALING_PATHWAY	0	0.75
Category members	GO Category	GO:0048011	neurotrophin TRK receptor signaling pathway	Database	0.63
Category members	Pathway	Pathway_795	REACTOME_REGULATION_OF_APOPTOSIS	0	0.31
Category members	GO Category	GO:0045893	positive regulation of transcription, DNA-dependent	Database	0.28
Category members	GO Category	GO:0043065	positive regulation of apoptotic process	Database	0.26
Category members	Pathway	Pathway_739	REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING	0	0.23
Category members	Pathway	Pathway_779	REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE	0	0.2
Category members	GO Category	GO:0050680	negative regulation of epithelial cell proliferation	Database	0.19
Category members	GO Category	GO:0006357	regulation of transcription from RNA polymerase II promoter	Database	0.19
Category members	GO Category	GO:0097190	apoptotic signaling pathway	Database	0.13
Category members	Pathway	Pathway_1140	REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK	0	0.1
Category members	Pathway	Pathway_557	PID_P75_NTR_PATHWAY	0	0.04
Category members	Pathway	Pathway_644	PID_TRKR_PATHWAY	0	0.04
Category members	GO Category	GO:0006355	regulation of transcription, DNA-dependent	Database	0
Category members	GO Category	GO:0043406	positive regulation of MAP kinase activity	Database	0