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Query: EPHA5

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EPHA5 0 1.323 -0.280 0.790

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
EPHA5 Ubiquitylation K657 0.533 _LKLPGK(gl)R_

Background Information for EPHA5:


Pubmed-EPHA5 »
Uniprot-EPHA5 »
Biogrid-EPHA5 »
ProteomicsDB-EPHA5 »

Tumorportal-EPHA5 »
COSMIC-EPHA5 »
GenomeRNAi-EPHA5 »
Genecards-EPHA5


Protein-protein Interactions for EPHA5
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait EFNB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSPAN3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in EPHA5
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Fibronectin_type3 IPR003961 0.19
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ephrin_rcpt_lig-bd_dom IPR001090 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members SAM IPR001660 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Galactose-bd-like IPR008979 0
Category members Growth_fac_rcpt_N_dom IPR009030 0
Category members SAM_2 IPR011510 0
Category members SAM/pointed IPR013761 0
Category members Tyr_kinase_ephrin_rcpt IPR016257 0
Category members Tyr_kinase_cat_dom IPR020635 0
Category members SAM_type1 IPR021129 0


Protein complexes (CORUM database) featuring EPHA5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring EPHA5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0032956 regulation of actin cytoskeleton organization Database 0.33
Category members GO Category GO:0030425 dendrite Database 0.26
Category members GO Category GO:0030424 axon Database 0.23
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members GO Category GO:0032314 regulation of Rac GTPase activity Database 0.11
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members Pathway Pathway_1034 KEGG_AXON_GUIDANCE 0 0.04
Category members GO Category GO:0005004 GPI-linked ephrin receptor activity Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members Pathway Pathway_665 PID_EPHA_FWDPATHWAY 0 0.01
Category members GO Category GO:0009897 external side of plasma membrane Database 0
Category members GO Category GO:0005003 ephrin receptor activity Database 0
Category members GO Category GO:0005005 transmembrane-ephrin receptor activity Database 0
Category members GO Category GO:0005791 rough endoplasmic reticulum Database 0
Category members GO Category GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0019933 cAMP-mediated signaling Database 0
Category members GO Category GO:0021766 hippocampus development Database 0
Category members GO Category GO:0032793 positive regulation of CREB transcription factor activity Database 0
Category members GO Category GO:0043025 neuronal cell body Database 0
Category members GO Category GO:0048013 ephrin receptor signaling pathway Database 0
Category members GO Category GO:0048666 neuron development Database 0
Category members GO Category GO:0051964 negative regulation of synapse assembly Database 0
Category members GO Category GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus Database 0


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