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Query: EHMT2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EHMT2 0 4.487 -0.600 0.200 0.016 0.287
EHMT2 0 4.487 -0.600 0.200 0.152 0.633 0.298

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
EHMT2 Phosphorylation S197 0.772 _MSMTGAGKS(ph)PPSVQSLAMR_
EHMT2 Ubiquitylation K1104 0.804 0.344 _TAK(gl)MGWGVR_
EHMT2 Phosphorylation T612 -0.754 _GDGVT(ph)PPAGTAAPAPPPLSQDVPGR_
EHMT2 Phosphorylation S230 -1.006 -1.118 _LLSMPGAQGAAAAGSEPPPATTS(ph)PEGQPK_
EHMT2 Phosphorylation T228 -0.955 _LLSM(ox)PGAQGAAAAGSEPPPAT(ph)TSPEGQPK_
EHMT2 Phosphorylation T229 -1.090 _LLSM(ox)PGAQGAAAAGSEPPPATT(ph)SPEGQPK_
EHMT2 Phosphorylation S289 0.981 _LNS(ph)GGGLSEELGSAR_
EHMT2 Ubiquitylation K939 -0.985 _NK(gl)EGDTAWDLTPER_

Background Information for EHMT2:


Pubmed-EHMT2 »
Uniprot-EHMT2 »
Biogrid-EHMT2 »
ProteomicsDB-EHMT2 »

Tumorportal-EHMT2 »
COSMIC-EHMT2 »
GenomeRNAi-EHMT2 »
Genecards-EHMT2


Protein-protein Interactions for EHMT2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BUB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CBX1 Cat. description Hein, Mann, Cell 2015
Category members IP bait EZH2 Cat. description Hein, Mann, Cell 2015
Category members IP bait HDAC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPF Cat. description Hein, Mann, Cell 2015
Category members IP bait MAX Cat. description Hein, Mann, Cell 2015
Category members IP bait TPM4 Cat. description Hein, Mann, Cell 2015
Category members IP bait WIZ Cat. description Hein, Mann, Cell 2015
Category members IP bait ZNF644 Cat. description Hein, Mann, Cell 2015
Category members IP bait CTBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HDAC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H2BA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait L3MBTL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MIER2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SIRT6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SUV39H1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SUV39H2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait XAGE2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait XAGE3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZBTB46 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF211 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF223 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF462 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in EHMT2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members SET_dom IPR001214 0.29
Category members Ankyrin_rpt IPR002110 0
Category members Pre-SET_Zn-bd_sub IPR003606 0
Category members Pre-SET_dom IPR007728 0
Category members Ankyrin_rpt-contain_dom IPR020683 0


Protein complexes (CORUM database) featuring EHMT2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 642 CtBP complex Database 3.6
Category members Corum 643 CtBP core complex Database 1.41
Category members Corum 860 DNMT1-G9a-PCNA complex Database 0.82
Category members Corum 862 DNMT1-G9a complex Database 0.33


Categories featuring EHMT2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members Pathway Pathway_348 REACTOME_TRANSCRIPTION 0 9
Category members Pathway Pathway_351 REACTOME_RNA_POL_I_TRANSCRIPTION 0 8.31
Category members Pathway Pathway_350 REACTOME_RNA_POL_I_RNA_POL_III_AND_MITOCHONDRIAL_TRANSCRIPTION 0 7.97
Category members GO Category GO:0005694 chromosome Database 3.87
Category members Pathway Pathway_346 REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION 0 3.42
Category members GO Category GO:0002039 p53 binding Database 2.06
Category members GO Category GO:0034968 histone lysine methylation Database 1.1
Category members GO Category GO:0010424 DNA methylation on cytosine within a CG sequence Database 0.98
Category members Pathway Pathway_308 PID_AR_TF_PATHWAY 0 0.86
Category members Pathway Pathway_22 KEGG_LYSINE_DEGRADATION 0 0.8
Category members GO Category GO:0018024 histone-lysine N-methyltransferase activity Database 0.73
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0046976 histone methyltransferase activity (H3-K27 specific) Database 0.29
Category members GO Category GO:0046974 histone methyltransferase activity (H3-K9 specific) Database 0.28
Category members GO Category GO:0006306 DNA methylation Database 0.22
Category members GO Category GO:0018027 peptidyl-lysine dimethylation Database 0.22
Category members GO Category GO:0006275 regulation of DNA replication Database 0.14
Category members GO Category GO:0016571 histone methylation Database 0.08
Category members GO Category GO:0016279 protein-lysine N-methyltransferase activity Database 0.04
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0007130 synaptonemal complex assembly Database 0
Category members GO Category GO:0007286 spermatid development Database 0
Category members GO Category GO:0009566 fertilization Database 0
Category members GO Category GO:0035265 organ growth Database 0


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