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Query: AMOT

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
AMOT 0 1.873 1.330 -0.510
AMOT 0 1.873 1.330 -0.510 0.614 0.467 0.043

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
AMOT Ubiquitylation K113 -0.211 0.313 _MQNNEELPTYEEAK(gl)VQSQYFR_
AMOT Phosphorylation S712 0.161 0.250 _DTTVIS(ph)HSPNTSYDTALEAR_
AMOT Phosphorylation S714 0.324 0.183 _DTTVISHS(ph)PNTSYDTALEAR_
AMOT Ubiquitylation K94 -0.138 _QEPQGQEIQSENLIMEK(gl)QLSPR_
AMOT Ubiquitylation K503 -0.204 _NK(gl)LEGEIR_

Background Information for AMOT:


Pubmed-AMOT »
Uniprot-AMOT »
Biogrid-AMOT »
ProteomicsDB-AMOT »

Tumorportal-AMOT »
COSMIC-AMOT »
GenomeRNAi-AMOT »
Genecards-AMOT


Protein-protein Interactions for AMOT
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AMOT Cat. description Hein, Mann, Cell 2015
Category members IP bait ALOX5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAGEA4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MPP5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB3IL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNF166 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WWP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in AMOT
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Angiomotin IPR009114 0.05
Category members Angiomotin_C IPR024646 0.05
Category members Prefoldin IPR009053 0


Protein complexes (CORUM database) featuring AMOT
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 848 RICH1/AMOT polarity complex, Flag-Amot precipitated Database 0.35
Category members Corum 846 RICH1/AMOT polarity complex, Flag-Rich1 precipitated Database 0


Categories featuring AMOT
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0030027 lamellipodium Database 1.77
Category members GO Category GO:0008180 COP9 signalosome Database 1.47
Category members GO Category GO:0030036 actin cytoskeleton organization Database 1.08
Category members GO Category GO:0005923 tight junction Database 0.69
Category members GO Category GO:0035329 hippo signaling Database 0.68
Category members Pathway Pathway_1013 REACTOME_SIGNALING_BY_HIPPO 0 0.63
Category members GO Category GO:0030334 regulation of cell migration Database 0.61
Category members GO Category GO:0001726 ruffle Database 0.33
Category members GO Category GO:0007043 cell-cell junction assembly Database 0.31
Category members GO Category GO:0003365 establishment of cell polarity involved in ameboidal cell migration Database 0.27
Category members GO Category GO:0043532 angiostatin binding Database 0.27
Category members GO Category GO:0051056 regulation of small GTPase mediated signal transduction Database 0.25
Category members GO Category GO:0001701 in utero embryonic development Database 0.2
Category members GO Category GO:0009986 cell surface Database 0.17
Category members GO Category GO:0043536 positive regulation of blood vessel endothelial cell migration Database 0.09
Category members GO Category GO:0006935 chemotaxis Database 0.09
Category members GO Category GO:0005884 actin filament Database 0.08
Category members GO Category GO:0034613 cellular protein localization Database 0.04
Category members GO Category GO:0001725 stress fiber Database 0.04
Category members GO Category GO:0009897 external side of plasma membrane Database 0
Category members GO Category GO:0001570 vasculogenesis Database 0
Category members GO Category GO:0001702 gastrulation with mouth forming second Database 0
Category members GO Category GO:0004872 receptor activity Database 0
Category members GO Category GO:0016525 negative regulation of angiogenesis Database 0
Category members GO Category GO:0030139 endocytic vesicle Database 0
Category members GO Category GO:0031410 cytoplasmic vesicle Database 0
Category members GO Category GO:0034260 negative regulation of GTPase activity Database 0
Category members GO Category GO:0040019 positive regulation of embryonic development Database 0
Category members GO Category GO:0042074 cell migration involved in gastrulation Database 0
Category members GO Category GO:0043116 negative regulation of vascular permeability Database 0
Category members GO Category GO:0043534 blood vessel endothelial cell migration Database 0
Category members GO Category GO:0045793 positive regulation of cell size Database 0
Category members GO Category GO:0048514 blood vessel morphogenesis Database 0
Category members GO Category GO:0051496 positive regulation of stress fiber assembly Database 0


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