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PID_ALK1_PATHWAY
(Pathway_995)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
PPP1CA 3 2.150 -0.860
PPP1CA 3 2.150 -0.860 -0.250 0.634 0.981 -0.108 0.171
ARRB2 1 2.000 -1.160 -0.340 0.096 0.051 -1.604
FKBP1A 0 -1.160 1.580
FKBP1A 0 1.040 -0.810
MAPK3 0
TGFB1 0 -0.550 1.050
CAV1 0 1.150 -0.150
CAV1 0 1.150 -0.150
CAV1 0 1.150 -0.150
TGFBR1 0 -0.260 0.020
SMAD5 0 0.640 -0.430
TGFB3 0 0.900 -0.540
SMAD4 0 0.420 -0.390 0.020 0.556 -0.485
CSNK2B 0 1.680 -0.760 0.254 -0.316 1.419 -0.407 -0.001

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ARRB2 Ubiquitylation K199 -1.933 _VQFAPEK(gl)PGPQPSAETTR_
CAV1 Ubiquitylation K5 0.591 0.963 _(ac)SGGK(gl)YVDSEGHLYTVPIR_
CAV1 Phosphorylation S6 0.836 0.688 _(ac)ADELS(ph)EKQVYDAHTK_
CAV1 Ubiquitylation K8 0.244 0.734 _(ac)ADELSEK(gl)QVYDAHTK_
CAV1 Ubiquitylation K26 0.724 0.894 _EQGNIYK(gl)PNNK_
CAV1 Ubiquitylation K30 -0.008 0.317 _EQGNIYKPNNK(gl)AMADELSEK_
CAV1 Ubiquitylation K39 0.690 1.170 _AMADELSEK(gl)QVYDAHTK_
CAV1 Phosphorylation S76 0.607 0.527 _AMADELS(ph)EK_
CAV1 Ubiquitylation K176 -0.259 _INLQK(gl)EI_
CSNK2B Phosphorylation S224 0.032 0.181 _IHPM(ox)AYQLQLQAAS(ph)NFKSPVK_
CSNK2B Phosphorylation S228 0.032 -0.025 _IHPM(ox)AYQLQLQAASNFKS(ph)PVK_
CSNK2B Ubiquitylation K231 -1.221 _SPVK(gl)TIR_
FKBP1A Ubiquitylation K72 1.074 _RGQTCVVHYTGM(ox)LEDGK(gl)K_
FKBP1A Ubiquitylation K73 0.453 _RGQTCVVHYTGM(ox)LEDGK(gl)K_
FKBP1A Ubiquitylation K90 0.605 1.010 _FM(ox)LGK(gl)QEVIR_
MAPK3 Phosphorylation Y204 -0.807 -2.487 _IADPEHDHTGFLTEY(ph)VATR_
MAPK3 Ubiquitylation K289 -0.608 _NYLQSLPSKTK(gl)_
PPP1CA Ubiquitylation K6 0.594 0.414 _(ac)SDSEK(gl)LNLDSIIGR_
PPP1CA Ubiquitylation K50 -0.131 0.478 _GLCLK(gl)SR_
PPP1CA Ubiquitylation K150 0.321 0.619 _IYGFYDECK(gl)RR_
PPP1CA Ubiquitylation K156 0.883 1.047 _YNIK(gl)LWK_
PPP1CA Ubiquitylation K247 0.313 _FLHK(gl)HDLDLICR_
PPP1CA Ubiquitylation K269 2.628 2.591 _AHQVVEDGYEFFAK(gl)R_
SMAD5 Ubiquitylation K64 -2.082 -1.647 _ALSSPGQPSK(gl)CVTIPR_
TGFB1 Ubiquitylation K50 -0.557 _GQILSK(gl)LR_
TGFB3 Ubiquitylation K50 -0.557 _GQILSK(gl)LR_
TGFBR1 Ubiquitylation K449 -0.991 _VVCEQK(gl)LRPNIPNR_
TGFBR1 Ubiquitylation K502 0.553 0.430 _TLSQLSQQEGIK(gl)M_


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