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Results for the Category
REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC
(Pathway_766)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
PDIA3 2 -2.160 3.830 0.411 2.714 -0.864 0.952 0.794
PDIA3 2 -2.160 3.830 0.189 2.142 -1.800
HSPA5 1 -0.670 0.310 -0.181 -0.208 0.339 -0.702 -0.192
SEC23A 1 -1.970 3.860 0.314 0.139 -0.515
HLA-B 1 0.000 -0.310 0.604 0.718
HLA-B 1 0.000 -0.310 -0.626
HLA-B 1 0.000 -0.310 1.149
HLA-B 1 0.000 -0.310
HLA-B 1 0.000 -0.310
CANX 0 0.090 -0.410 0.234 -0.021 -1.207 -0.098 -0.313
SEC31A 0 1.690 -1.010 -0.161 -0.171 0.128
SEC24B 0 -0.430 0.680 -0.093 -0.387
SAR1B 0 -1.030 1.290 -0.088 0.687 0.548
SEC13 0 -0.290 0.170 1.171 0.795 0.493 -0.623 0.018
TAP1 0 -1.000 1.040
SEC24C 0 0.420 -0.360 -0.393
CALR 0 -1.300 2.220 0.480 0.054
TAP2 0 -0.940 1.130
HLA-C 0 0.604 0.718
HLA-C 0
HLA-C 0
HLA-A 0 0.790 -0.840 -0.626
HLA-C 0 -0.626
HLA-F 0 0.020 -0.190 -0.626
HLA-G 0 0.000 0.140 -0.626
HLA-A 0 0.790 -0.840 1.149
HLA-C 0 1.149
HLA-A 0 0.790 -0.840

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
CALR Ubiquitylation K48 0.703 _SDFGK(gl)FVLSSGK_
CALR Ubiquitylation K153 -0.924 0.619 _GK(gl)NVLINK_
CALR Ubiquitylation K159 -1.004 0.381 _NVLINK(gl)DIR_
CANX Ubiquitylation K96 -1.324 _VTYK(gl)APVPTGEVYFADSFDR_
CANX Ubiquitylation K122 0.021 0.828 _GTLSGWILSK(gl)AK_
CANX Ubiquitylation K124 -0.479 _GTLSGWILSKAK(gl)_
CANX Ubiquitylation K153 -0.762 _LPGDK(gl)GLVLMSR_
CANX Ubiquitylation K252 0.015 _TGIYEEK(gl)HAK_
CANX Ubiquitylation K268 1.422 _TYFTDK(gl)K_
CANX Ubiquitylation K415 -1.726 _CESAPGCGVWQRPVIDNPNYK(gl)GK_
CANX Ubiquitylation K417 -0.679 _PVIDNPNYKGK(gl)_
CANX Ubiquitylation K494 -0.002 1.403 _IVDDWANDGWGLKK(gl)_
CANX Phosphorylation S589 0.479 0.421 _S(ph)DAEEDGGTVSQEEEDR_
CANX Phosphorylation T597 0.469 0.188 _SDAEEDGGT(ph)VSQEEEDRKPK_
CANX Phosphorylation S599 0.395 0.352 _SDAEEDGGTVS(ph)QEEEDR_
CANX Phosphorylation S618 0.442 0.320 _AEEDEILNRS(ph)PR_
HLA-A Ubiquitylation K92 -0.349 _NVK(gl)AQSQTDRVDLGTLR_
HLA-A Ubiquitylation K168 0.549 _SWTAADMAAQITK(gl)R_
HLA-A Ubiquitylation K346 -0.072 -0.211 _K(gl)GGSYTQAASSDSAQGSDVSLTACK(gl)V_
HLA-A Ubiquitylation K370 0.345 0.434 _K(gl)GGSYTQAASSDSAQGSDVSLTACK(gl)V_
HLA-B Ubiquitylation K177 -0.088 _YLENGKDK(gl)LER_
HLA-B Ubiquitylation K267 -0.118 _TFQK(gl)WAAVVVPSGEEQR_
HLA-C Ubiquitylation K120 -0.876 _GYDQSAYDGK(gl)DYIALNEDLR_
HLA-C Ubiquitylation K341 -0.900 -0.092 _SSGGK(gl)GGSCSQAACSNSAQGSDESLITCK_
HSPA5 Ubiquitylation K81 -0.455 _LIGDAAK(gl)NQLTSNPENTVFDAK(gl)R_
HSPA5 Ubiquitylation K96 -0.392 -0.109 _NQLTSNPENTVFDAK(gl)R_
HSPA5 Ubiquitylation K118 0.783 _FLPFK(gl)VVEK_
HSPA5 Ubiquitylation K340 0.743 _STMK(gl)PVQK_
HSPA5 Ubiquitylation K352 -0.469 0.822 _VLEDSDLK(gl)K_
HSPA5 Ubiquitylation K353 -0.469 _VLEDSDLK(gl)K_
HSPA5 Ubiquitylation K447 3.097 _NTVVPTKK(gl)_
HSPA5 Ubiquitylation K523 -0.120 0.631 _NK(gl)ITITNDQNR_
PDIA3 Ubiquitylation K75 -0.105 _LK(gl)GIVPLAK_
PDIA3 Ubiquitylation K94 -0.012 0.658 _VDCTANTNTCNK(gl)YGVSGYPTLK_
PDIA3 Ubiquitylation K130 0.775 _TADGIVSHLKK(gl)_
PDIA3 Ubiquitylation K226 -0.163 0.525 _TVAYTEQK(gl)MTSGK_
PDIA3 Ubiquitylation K362 -0.242 _FLQDYFDGNLK(gl)R_
SEC24B Phosphorylation S1254 -0.049 _DSRPLS(ph)PILHIVKDESPAK_
SEC24C Ubiquitylation K956 -2.127 -1.632 _LLPLTK(gl)SPVESTTEPPAVR_
SEC31A Ubiquitylation K460 0.843 1.346 _SDQLQQAVQSQGFINYCQK(gl)K_
SEC31A Ubiquitylation K461 0.843 1.346 _SDQLQQAVQSQGFINYCQK(gl)K_
SEC31A Phosphorylation S527 -0.287 0.538 _DSDQVAQS(ph)DGEESPAAEEQLLGEHIK_
SEC31A Phosphorylation S799 -0.417 -0.388 _AQGEPVAGHES(ph)PKIPYEK_
SEC31A Ubiquitylation K806 -0.016 0.221 _IPYEK(gl)QQLPK_
SEC31A Ubiquitylation K1171 -0.024 -0.507 _CLSSATDPQTK(gl)R_
SEC31A Phosphorylation T1192 0.363 -1.264 _EQT(ph)LSPTITSGLHNIAR_
SEC31A Phosphorylation S1194 0.316 0.198 _EQTLS(ph)PTITSGLHNIAR_
SEC31A Ubiquitylation K1248 0.394 0.332 _VVLTQANK(gl)LGV_
TAP1 Ubiquitylation K449 1.133 _SFANEEGEAQK(gl)FR_
TAP1 Ubiquitylation K458 1.364 _LQEIK(gl)TLNQK_
TAP2 Ubiquitylation K246 -0.098 0.529 _QDLGFFQETK(gl)TGELNSR_
TAP2 Ubiquitylation K357 -1.129 0.474 _YK(gl)EALEQCR_
TAP2 Ubiquitylation K613 -1.176 _GSQLAAGQK(gl)QR_
TAP2 Ubiquitylation K683 -0.236 _LQK(gl)LAQLQEGQDLYSR_


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