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Query: SEC24C

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SEC24C 0 -4.153 0.420 -0.360 -0.393

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SEC24C Ubiquitylation K956 -2.127 -1.632 _LLPLTK(gl)SPVESTTEPPAVR_

Background Information for SEC24C:


Pubmed-SEC24C »
Uniprot-SEC24C »
Biogrid-SEC24C »
ProteomicsDB-SEC24C »

Tumorportal-SEC24C »
COSMIC-SEC24C »
GenomeRNAi-SEC24C »
Genecards-SEC24C


Protein-protein Interactions for SEC24C
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDC42 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CENPE Cat. description Hein, Mann, Cell 2015
Category members IP bait CENPQ Cat. description Hein, Mann, Cell 2015
Category members IP bait CLTC Cat. description Hein, Mann, Cell 2015
Category members IP bait GAK Cat. description Hein, Mann, Cell 2015
Category members IP bait GTSE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MIS12 Cat. description Hein, Mann, Cell 2015
Category members IP bait SEC16A Cat. description Hein, Mann, Cell 2015
Category members IP bait SEC24C Cat. description Hein, Mann, Cell 2015
Category members IP bait USO1 Cat. description Hein, Mann, Cell 2015


Protein Domains in SEC24C
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_Sec23_Sec24 IPR006895 0.13
Category members Sec23/24_trunk_dom IPR006896 0.13
Category members Sec23/24_helical_dom IPR006900 0.13
Category members Sec23_24_beta_S IPR012990 0.13
Category members Gelsolin-like_dom IPR007123 0.09
Category members VWF_A IPR002035 0


Protein complexes (CORUM database) featuring SEC24C
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SEC24C
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_764 REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION 0 2.56
Category members GO Category GO:0002474 antigen processing and presentation of peptide antigen via MHC class I Database 2.5
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members Pathway Pathway_474 REACTOME_MEMBRANE_TRAFFICKING 0 1.14
Category members Pathway Pathway_1265 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION 0 0.6
Category members Pathway Pathway_766 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC 0 0.47
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0006888 ER to Golgi vesicle-mediated transport Database 0.28
Category members GO Category GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II Database 0.13
Category members GO Category GO:0003674 molecular_function Database 0.08
Category members GO Category GO:0030127 COPII vesicle coat Database 0.08
Category members Pathway Pathway_115 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION 0 0
Category members Pathway Pathway_94 REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION 0 0
Category members Pathway Pathway_95 REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION 0 0
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0012507 ER to Golgi transport vesicle membrane Database 0
Category members GO Category GO:0018279 protein N-linked glycosylation via asparagine Database 0
Category members GO Category GO:0043687 post-translational protein modification Database 0
Category members GO Category GO:0048208 COPII vesicle coating Database 0


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