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Query: SEC31A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SEC31A 0 2.886 1.690 -1.010 -0.161 -0.171 0.128

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SEC31A Ubiquitylation K460 0.843 1.346 _SDQLQQAVQSQGFINYCQK(gl)K_
SEC31A Ubiquitylation K461 0.843 1.346 _SDQLQQAVQSQGFINYCQK(gl)K_
SEC31A Phosphorylation S527 -0.287 0.538 _DSDQVAQS(ph)DGEESPAAEEQLLGEHIK_
SEC31A Ubiquitylation K1248 0.394 0.332 _VVLTQANK(gl)LGV_
SEC31A Ubiquitylation K806 -0.016 0.221 _IPYEK(gl)QQLPK_
SEC31A Phosphorylation S1194 0.316 0.198 _EQTLS(ph)PTITSGLHNIAR_
SEC31A Phosphorylation S799 -0.417 -0.388 _AQGEPVAGHES(ph)PKIPYEK_
SEC31A Ubiquitylation K1171 -0.024 -0.507 _CLSSATDPQTK(gl)R_
SEC31A Phosphorylation T1192 0.363 -1.264 _EQT(ph)LSPTITSGLHNIAR_

Background Information for SEC31A:


Pubmed-SEC31A »
Uniprot-SEC31A »
Biogrid-SEC31A »
ProteomicsDB-SEC31A »

Tumorportal-SEC31A »
COSMIC-SEC31A »
GenomeRNAi-SEC31A »
Genecards-SEC31A


Protein-protein Interactions for SEC31A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SEC24C Cat. description Hein, Mann, Cell 2015
Category members IP bait TFG Cat. description Hein, Mann, Cell 2015
Category members IP bait GNPDA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SEC31A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SEC31A
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members WD40_repeat IPR001680 0.52


Protein complexes (CORUM database) featuring SEC31A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SEC31A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members GO Category GO:0015031 protein transport Database 3.48
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_764 REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION 0 2.56
Category members GO Category GO:0002474 antigen processing and presentation of peptide antigen via MHC class I Database 2.5
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0030968 endoplasmic reticulum unfolded protein response Database 1.35
Category members GO Category GO:0006987 activation of signaling protein activity involved in unfolded protein response Database 1.26
Category members Pathway Pathway_474 REACTOME_MEMBRANE_TRAFFICKING 0 1.14
Category members Pathway Pathway_147 REACTOME_UNFOLDED_PROTEIN_RESPONSE 0 1.08
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members Pathway Pathway_1265 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION 0 0.6
Category members Pathway Pathway_766 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC 0 0.47
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members Pathway Pathway_146 REACTOME_DIABETES_PATHWAYS 0 0.39
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0006888 ER to Golgi vesicle-mediated transport Database 0.28
Category members GO Category GO:0048306 calcium-dependent protein binding Database 0.17
Category members GO Category GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II Database 0.13
Category members Pathway Pathway_148 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S 0 0.11
Category members GO Category GO:0030127 COPII vesicle coat Database 0.08
Category members Pathway Pathway_115 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION 0 0
Category members Pathway Pathway_94 REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION 0 0
Category members Pathway Pathway_95 REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION 0 0
Category members GO Category GO:0012507 ER to Golgi transport vesicle membrane Database 0
Category members GO Category GO:0018279 protein N-linked glycosylation via asparagine Database 0
Category members GO Category GO:0030120 vesicle coat Database 0
Category members GO Category GO:0030134 ER to Golgi transport vesicle Database 0
Category members GO Category GO:0043687 post-translational protein modification Database 0
Category members GO Category GO:0048208 COPII vesicle coating Database 0
Category members GO Category GO:0051592 response to calcium ion Database 0


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