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Results for the Category
REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS
(Pathway_659)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
ITPR3 2 -0.190 -0.500 1.489 1.835
STIM1 2 0.060 -0.140 0.411 0.585
FYN 1 1.080 -1.100
FYN 1 1.080 -1.100
PLCG1 1 -0.170 0.000
CALM2 1 -0.690 0.700 1.911
CALM2 1 -0.690 0.700 0.877 -4.680
CALM3 1 -0.190 0.120 1.911
CALM3 1 -0.190 0.120 0.877 -4.680
CALM1 1 -0.440 0.360 1.911
CALM1 1 -0.440 0.360 0.877 -4.680
LYN 1 -1.790 3.770
LYN 1 -1.790 3.770
SOS1 0 0.500 -0.620 -0.570
ITPR2 0 -1.020 0.610 0.952 0.981
PIK3R1 0 1.910 -1.220 -0.441 0.147
SH3KBP1 0 -0.400 -0.020 -0.522
NCK1 0 -0.370 0.580
GRB2 0 -0.240 0.300 -1.021 0.057 0.906

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
CALM1 Ubiquitylation K78 0.061 _DGDGTITTK(gl)ELGTVMR_
CALM1 Ubiquitylation K142 0.922 _VFDK(gl)DGNGYISAAELR_
CALM2 Ubiquitylation K78 0.061 _DGDGTITTK(gl)ELGTVMR_
CALM2 Ubiquitylation K142 0.922 _VFDK(gl)DGNGYISAAELR_
CALM3 Ubiquitylation K78 0.061 _DGDGTITTK(gl)ELGTVMR_
CALM3 Ubiquitylation K142 0.922 _VFDK(gl)DGNGYISAAELR_
FYN Ubiquitylation K13 0.286 _DKEATK(gl)LTEER_
FYN Phosphorylation S21 0.373 0.731 _DGS(ph)LNQSSGYR_
FYN Ubiquitylation K259 0.921 _LTDLSVK(gl)TK_
FYN Ubiquitylation K261 0.099 _LTDLSVKTK(gl)_
FYN Ubiquitylation K273 6.025 _SLCLEKK(gl)_
FYN Ubiquitylation K275 -0.521 _ESLQLIK(gl)R_
GRB2 Ubiquitylation K10 0.146 _YDFK(gl)ATADDELSFK_
GRB2 Ubiquitylation K20 -0.078 _ATADDELSFK(gl)R_
GRB2 Ubiquitylation K69 -0.362 0.641 _AK(gl)AEEMLSK_
GRB2 Ubiquitylation K76 0.754 _AEEMLSK(gl)QR_
GRB2 Ubiquitylation K109 0.381 -0.002 _FGNDVQHFK(gl)VLR_
ITPR2 Ubiquitylation K909 -0.247 _LSK(gl)FQDGGNNVMR_
ITPR2 Phosphorylation S1160 0.443 0.895 _GGEEPIEESNILS(ph)PVQDGTK_
ITPR3 Ubiquitylation K529 1.377 _EK(gl)GGEGPLVR_
ITPR3 Phosphorylation S934 0.318 -0.802 _KQS(ph)VFSAPSLSAGASAAEPLDR_
ITPR3 Phosphorylation S937 -0.026 _KQSVFS(ph)APSLSAGASAAEPLDR_
ITPR3 Ubiquitylation K1534 -0.220 _TLAMVAK(gl)GR_
ITPR3 Phosphorylation S1832 0.650 0.560 _VAS(ph)FSIPGSSSR_
ITPR3 Ubiquitylation K2597 -0.819 _NK(gl)NLDWFPR_
ITPR3 Ubiquitylation K2628 -0.010 _ILQDK(gl)LNSTMK_
ITPR3 Phosphorylation S2670 1.132 1.555 _LGFVDVQNCIS(ph)R_
LYN Ubiquitylation K20 -0.592 _GKDSLSDDGVDLK(gl)TQPVR_
LYN Ubiquitylation K40 0.100 _DPTSNK(gl)QQRPVPESQLLPGQR_
LYN Phosphorylation S104 0.944 0.841 _DSLS(ph)DDGVDLK_
LYN Ubiquitylation K213 0.441 _HYQK(gl)QADGLCR_
LYN Ubiquitylation K477 -0.191 _VENCPDELYDIMK(gl)MCWK_
NCK1 Phosphorylation S85 -0.027 -0.877 _RKPS(ph)VPDSASPADDSFVDPGER_
NCK1 Phosphorylation S91 0.493 _RKPSVPDSAS(ph)PADDSFVDPGER_
PLCG1 Ubiquitylation K300 8.031 _DLK(gl)NMLSQVNYR_
PLCG1 Ubiquitylation K348 -0.219 _SLMYSAQK(gl)TMDLPFLEASTLR_
PLCG1 Ubiquitylation K552 -0.355 _NMAQYFK(gl)K_
PLCG1 Ubiquitylation K553 -0.355 _NMAQYFK(gl)K_
PLCG1 Ubiquitylation K1063 0.864 0.355 _LTEGK(gl)IMER_
PLCG1 Phosphorylation S1370 0.475 0.515 _AREGS(ph)FESR_
SH3KBP1 Phosphorylation S230 0.300 0.186 _S(ph)IEVENDFLPVEK_
SOS1 Phosphorylation S1082 0.278 _IPESETESTASAPNS(ph)PR_
SOS1 Phosphorylation S1166 0.097 -0.094 _RPESAPAES(ph)SPSK_
STIM1 Phosphorylation S257 2.583 2.199 _AEQS(ph)LHDLQER_
STIM1 Phosphorylation S625 0.301 0.697 _DLTHS(ph)DSESSLHMSDR_
STIM1 Phosphorylation S627 2.398 _DLTHSDS(ph)ESSLHMSDR_
STIM1 Phosphorylation S681 -0.610 -1.215 _LPDS(ph)PALAK_
STIM1 Phosphorylation S714 -0.114 -0.742 _AHSLM(ox)ELSPSAPPGGS(ph)PHLDSSR_
STIM1 Phosphorylation S722 -1.253 _S(ph)HSPSSPDPDTPSPVGDSR_
STIM1 Phosphorylation S724 -1.098 -1.197 _SHS(ph)PSSPDPDTPSPVGDSR_
STIM1 Phosphorylation S773 -1.082 _AVAEEDNGSIGEETDS(ph)SPGR_
STIM1 Phosphorylation S774 0.067 _KAVAEEDNGSIGEETDSS(ph)PGRK_


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