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Query: STIM1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
STIM1 2 5.977 0.060 -0.140 0.411 0.585

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
STIM1 Phosphorylation S627 2.398 _DLTHSDS(ph)ESSLHMSDR_
STIM1 Phosphorylation S257 2.583 2.199 _AEQS(ph)LHDLQER_
STIM1 Phosphorylation S625 0.301 0.697 _DLTHS(ph)DSESSLHMSDR_
STIM1 Phosphorylation S714 -0.114 -0.742 _AHSLM(ox)ELSPSAPPGGS(ph)PHLDSSR_
STIM1 Phosphorylation S724 -1.098 -1.197 _SHS(ph)PSSPDPDTPSPVGDSR_
STIM1 Phosphorylation S681 -0.610 -1.215 _LPDS(ph)PALAK_
STIM1 Phosphorylation S722 -1.253 _S(ph)HSPSSPDPDTPSPVGDSR_
STIM1 Phosphorylation S773 -1.082 _AVAEEDNGSIGEETDS(ph)SPGR_
STIM1 Phosphorylation S774 0.067 _KAVAEEDNGSIGEETDSS(ph)PGRK_

Background Information for STIM1:


Pubmed-STIM1 »
Uniprot-STIM1 »
Biogrid-STIM1 »
ProteomicsDB-STIM1 »

Tumorportal-STIM1 »
COSMIC-STIM1 »
GenomeRNAi-STIM1 »
Genecards-STIM1


Protein-protein Interactions for STIM1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCDC40 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD1E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HAUS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL17RB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRRTM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait METTL6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC39A9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STIM2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in STIM1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members SAM IPR001660 0
Category members SAM_2 IPR011510 0
Category members SAM/pointed IPR013761 0
Category members SAM_type1 IPR021129 0


Protein complexes (CORUM database) featuring STIM1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring STIM1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0043234 protein complex Database 2.73
Category members Pathway Pathway_660 REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR 0 2.12
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0030426 growth cone Database 1.61
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0005874 microtubule Database 1.21
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0051010 microtubule plus-end binding Database 0.47
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members Pathway Pathway_1188 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS 0 0.32
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members Pathway Pathway_1201 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS 0 0.18
Category members Pathway Pathway_705 PID_CD8_TCR_PATHWAY 0 0.17
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members GO Category GO:0051924 regulation of calcium ion transport Database 0.11
Category members GO Category GO:0005513 detection of calcium ion Database 0.1
Category members Pathway Pathway_285 REACTOME_PLATELET_HOMEOSTASIS 0 0.08
Category members Pathway Pathway_687 PID_TCR_PATHWAY 0 0.08
Category members Pathway Pathway_659 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS 0 0
Category members GO Category GO:0005246 calcium channel regulator activity Database 0
Category members GO Category GO:0006812 cation transport Database 0
Category members GO Category GO:0006816 calcium ion transport Database 0
Category members GO Category GO:0015279 store-operated calcium channel activity Database 0
Category members GO Category GO:0030176 integral to endoplasmic reticulum membrane Database 0
Category members GO Category GO:0032237 activation of store-operated calcium channel activity Database 0
Category members GO Category GO:0032541 cortical endoplasmic reticulum Database 0


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