Results for the Category
KEGG_CYTOSOLIC_DNA_SENSING_PATHWAY
(Pathway_354)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| POLR3A | 1 | -0.550 | 1.310 | -0.221 | 0.400 | 0.226 | ||
| ADAR | 1 | -0.700 | 1.260 | -0.595 | -2.524 | -1.253 | -1.530 | -0.195 |
| ADAR | 1 | -0.700 | 1.260 | 0.674 | -0.016 | |||
| POLR1D | 1 | -1.180 | 1.710 | 3.224 | ||||
| POLR1D | 1 | -0.480 | 1.030 | 3.224 | ||||
| POLR3B | 0 | 0.540 | -0.900 | 1.056 | 0.594 | |||
| MAVS | 0 | 1.610 | -0.380 | -1.056 | -0.630 | |||
| IKBKB | 0 | 0.400 | 0.610 | |||||
| NFKB1 | 0 | 0.720 | -0.810 | |||||
| IRF3 | 0 | -0.190 | -0.050 | |||||
| POLR3F | 0 | 0.270 | -0.630 | |||||
| RIPK1 | 0 | -0.190 | 0.440 | |||||
| POLR3D | 0 | -0.570 | 0.130 | |||||
| POLR1C | 0 | -1.340 | 1.750 | -0.547 | 0.025 | -0.150 | 0.246 | 0.218 |
| RELA | 0 | -1.130 | 1.600 | 0.793 | ||||
| TMEM173 | 0 | -0.800 | 0.340 | |||||
| CHUK | 0 | -0.480 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| ADAR | Ubiquitylation | K427 | -0.338 | _NTNSVPETAPAAIPETK(gl)R_ | |
| ADAR | Phosphorylation | T644 | 2.146 | 1.082 | _TAESQT(ph)PTPSATSFFSGK_ |
| ADAR | Phosphorylation | S657 | 0.046 | _S(ph)PVTTLLECMHK_ | |
| ADAR | Ubiquitylation | K680 | -0.527 | _LLSK(gl)EGPAHEPK_ | |
| ADAR | Ubiquitylation | K841 | 1.158 | _VLIGENEK(gl)AER_ | |
| ADAR | Phosphorylation | S866 | 0.195 | _TMLLLS(ph)RSPEAQPK_ | |
| ADAR | Ubiquitylation | K987 | -0.367 | _DSIFEPAK(gl)GGEK_ | |
| ADAR | Ubiquitylation | K991 | -0.367 | _DSIFEPAK(gl)GGEK_ | |
| ADAR | Ubiquitylation | K1158 | 1.002 | 0.569 | _VSIYDSK(gl)R_ |
| CHUK | Ubiquitylation | K296 | -1.637 | _GGPVDLTLK(gl)QPR_ | |
| IKBKB | Ubiquitylation | K106 | 0.253 | _K(gl)YLNQFENCCGLR_ | |
| IKBKB | Phosphorylation | S672 | 0.670 | 0.244 | _GPVSGS(ph)PDSMNASR_ |
| IRF3 | Phosphorylation | S173 | -0.663 | -1.111 | _S(ph)PSLDNPTPFPNLGPSENPLK_ |
| IRF3 | Phosphorylation | S175 | -0.663 | -0.661 | _S(ph)PSLDNPTPFPNLGPSENPLKR_ |
| IRF3 | Ubiquitylation | K193 | -3.309 | -3.157 | _SPSLDNPTPFPNLGPSENPLK(gl)R_ |
| MAVS | Phosphorylation | S152 | 0.146 | -0.466 | _EKEPSYPMPVQETQAPES(ph)PGENSEQALQTLSPR_ |
| MAVS | Phosphorylation | S165 | -0.888 | _EKEPSYPMPVQETQAPESPGENSEQALQTLS(ph)PR_ | |
| MAVS | Phosphorylation | S222 | 1.349 | 1.006 | _GPVS(ph)PSVSFQPLAR_ |
| MAVS | Ubiquitylation | K362 | 0.082 | _AGMVPSK(gl)VPTSMVLTK_ | |
| NFKB1 | Phosphorylation | S907 | -0.025 | 0.113 | _TTSQAHSLPLS(ph)PASTR_ |
| POLR1C | Ubiquitylation | K167 | -0.721 | _DSSDPNELYVNHK(gl)VYTR_ | |
| POLR1C | Ubiquitylation | K332 | -0.542 | _VLMGK(gl)CR_ | |
| POLR1D | Ubiquitylation | K15 | -0.683 | _ISGLK(gl)TSMAEGER_ | |
| POLR3A | Ubiquitylation | K398 | 0.278 | _VNK(gl)ANINFLR_ | |
| POLR3A | Ubiquitylation | K439 | -0.169 | _EK(gl)MAQELK_ | |
| POLR3A | Ubiquitylation | K713 | -2.239 | _AK(gl)YELLNAGYK_ | |
| POLR3A | Ubiquitylation | K974 | 3.079 | _FIK(gl)GVSEK_ | |
| POLR3A | Ubiquitylation | K1242 | 0.246 | -0.360 | _AVM(ox)ATHGVK(gl)GTR_ |
| POLR3B | Ubiquitylation | K404 | 1.232 | _AAQFDVVK(gl)HMR_ | |
| POLR3B | Ubiquitylation | K968 | 0.649 | 0.285 | _FHYGTAFGGSK(gl)VK_ |
| POLR3D | Ubiquitylation | K152 | -0.596 | _ETDEETK(gl)QILR_ | |
| POLR3F | Ubiquitylation | K199 | -0.038 | _ESK(gl)QNPMIQR_ | |
| RIPK1 | Ubiquitylation | K642 | -0.431 | _EGIK(gl)GATVGK_ | |
| TMEM173 | Ubiquitylation | K289 | 0.324 | _EDRLEQAK(gl)LFCR_ | |
| TMEM173 | Phosphorylation | S358 | 0.609 | _TSAVPSTSTMS(ph)QEPELLISGMEKPLPLR_ |
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