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Query: TMEM173

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TMEM173 0 1.273 -0.800 0.340

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TMEM173 Phosphorylation S358 0.609 _TSAVPSTSTMS(ph)QEPELLISGMEKPLPLR_
TMEM173 Ubiquitylation K289 0.324 _EDRLEQAK(gl)LFCR_

Background Information for TMEM173:


Pubmed-TMEM173 »
Uniprot-TMEM173 »
Biogrid-TMEM173 »
ProteomicsDB-TMEM173 »

Tumorportal-TMEM173 »
COSMIC-TMEM173 »
GenomeRNAi-TMEM173 »
Genecards-TMEM173


Protein-protein Interactions for TMEM173
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait TMEM173 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TMEM173
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring TMEM173
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TMEM173
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0031625 ubiquitin protein ligase binding Database 2.54
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0030659 cytoplasmic vesicle membrane Database 0.62
Category members GO Category GO:0032481 positive regulation of type I interferon production Database 0.54
Category members GO Category GO:0005741 mitochondrial outer membrane Database 0.46
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0051607 defense response to virus Database 0.07
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members GO Category GO:0033160 positive regulation of protein import into nucleus, translocation Database 0.04
Category members GO Category GO:0032479 regulation of type I interferon production Database 0.04
Category members Pathway Pathway_354 KEGG_CYTOSOLIC_DNA_SENSING_PATHWAY 0 0
Category members Pathway Pathway_483 KEGG_RIG_I_LIKE_RECEPTOR_SIGNALING_PATHWAY 0 0
Category members GO Category GO:0002218 activation of innate immune response Database 0
Category members GO Category GO:0002230 positive regulation of defense response to virus by host Database 0
Category members GO Category GO:0005777 peroxisome Database 0
Category members GO Category GO:0032092 positive regulation of protein binding Database 0
Category members GO Category GO:0032608 interferon-beta production Database 0
Category members GO Category GO:0035458 cellular response to interferon-beta Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0042993 positive regulation of transcription factor import into nucleus Database 0
Category members GO Category GO:0071360 cellular response to exogenous dsRNA Database 0


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