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Query: POLR1D

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
POLR1D 1 4.251 -1.180 1.710 3.224
POLR1D 1 4.251 -0.480 1.030 3.224

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
POLR1D Ubiquitylation K15 -0.683 _ISGLK(gl)TSMAEGER_

Background Information for POLR1D:


Pubmed-POLR1D »
Uniprot-POLR1D »
Biogrid-POLR1D »
ProteomicsDB-POLR1D »

Tumorportal-POLR1D »
COSMIC-POLR1D »
GenomeRNAi-POLR1D »
Genecards-POLR1D


Protein-protein Interactions for POLR1D
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDC42 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK8 Cat. description Hein, Mann, Cell 2015
Category members IP bait POLR1A Cat. description Hein, Mann, Cell 2015
Category members IP bait POLR2F Cat. description Hein, Mann, Cell 2015
Category members IP bait GPN3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POLR1C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POLR3D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POLR3GL Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in POLR1D
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RBP11-like_dimer IPR009025 0.02


Protein complexes (CORUM database) featuring POLR1D
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5233 TNF-alpha/NF-kappa B signaling complex 5 Database 0.29


Categories featuring POLR1D
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_348 REACTOME_TRANSCRIPTION 0 9
Category members Pathway Pathway_351 REACTOME_RNA_POL_I_TRANSCRIPTION 0 8.31
Category members Pathway Pathway_350 REACTOME_RNA_POL_I_RNA_POL_III_AND_MITOCHONDRIAL_TRANSCRIPTION 0 7.97
Category members Pathway Pathway_346 REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION 0 3.42
Category members GO Category GO:0006360 transcription from RNA polymerase I promoter Database 2.66
Category members GO Category GO:0006361 transcription initiation from RNA polymerase I promoter Database 2.41
Category members Pathway Pathway_345 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION 0 1.9
Category members GO Category GO:0006363 termination of RNA polymerase I transcription Database 1.71
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006362 transcription elongation from RNA polymerase I promoter Database 1.47
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0001054 RNA polymerase I activity Database 1.02
Category members GO Category GO:0001056 RNA polymerase III activity Database 1.02
Category members Pathway Pathway_349 KEGG_RNA_POLYMERASE 0 0.91
Category members GO Category GO:0005736 DNA-directed RNA polymerase I complex Database 0.78
Category members GO Category GO:0032481 positive regulation of type I interferon production Database 0.54
Category members Pathway Pathway_355 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER 0 0.37
Category members Pathway Pathway_353 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION 0 0.29
Category members Pathway Pathway_357 REACTOME_RNA_POL_III_TRANSCRIPTION 0 0.29
Category members GO Category GO:0005666 DNA-directed RNA polymerase III complex Database 0.29
Category members Pathway Pathway_356 REACTOME_RNA_POL_III_CHAIN_ELONGATION 0 0.23
Category members Pathway Pathway_68 KEGG_PURINE_METABOLISM 0 0.23
Category members Pathway Pathway_277 KEGG_PYRIMIDINE_METABOLISM 0 0.18
Category members GO Category GO:0006383 transcription from RNA polymerase III promoter Database 0.18
Category members GO Category GO:0006385 transcription elongation from RNA polymerase III promoter Database 0.18
Category members GO Category GO:0006386 termination of RNA polymerase III transcription Database 0.18
Category members Pathway Pathway_347 BIOCARTA_ARF_PATHWAY 0 0.12
Category members Pathway Pathway_352 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER 0 0.11
Category members Disease phenotype Treacher-Collins_syndrome Treacher-Collins syndrome Database 0.09
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members Pathway Pathway_354 KEGG_CYTOSOLIC_DNA_SENSING_PATHWAY 0 0
Category members GO Category GO:0046983 protein dimerization activity Database 0


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