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REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION
(Pathway_1147)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
HSP90AA1 3 -0.150 0.150 0.395 1.024 -1.280 0.611 0.460
HSP90AA1 3 0.170 -0.420 0.395 1.024 -1.280 0.611 0.460
FYN 1 1.080 -1.100
FYN 1 1.080 -1.100
HSP90AB1 1 1.280 -1.050 0.283 0.786 -1.175 0.317 0.463
PLXNA3 1 -0.130 0.400
CFL1 1 0.725 0.148 -0.943
PLXNA2 0 -1.160 1.870 0.107 0.180
PLXNA2 0 1.880 -0.800 0.107 0.180
NRP1 0 0.880 -0.670 0.909 0.353
PLXNA1 0 0.330 0.040 -0.130 0.142 0.555
RAC1 0 -0.580 1.580 0.486 -0.364 -0.568
PAK1 0 1.190 -0.630
PAK2 0 -0.760 1.040

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
CFL1 Phosphorylation S41 0.781 0.338 _(ac)AS(ph)GVAVSDGVIK_
CFL1 Ubiquitylation K57 0.538 0.318 _VFNDMK(gl)VR_
CFL1 Ubiquitylation K82 1.563 _AVLFCLSEDK(gl)K_
CFL1 Ubiquitylation K83 1.163 _AVLFCLSEDKK(gl)_
CFL1 Ubiquitylation K116 0.583 _MLPDK(gl)DCR_
CFL1 Ubiquitylation K130 0.398 0.825 _YALYDATYETK(gl)ESK_
CFL1 Ubiquitylation K133 0.441 _YALYDATYETKESK(gl)_
CFL1 Ubiquitylation K152 0.783 0.508 _SK(gl)MIYASSK_
CFL1 Ubiquitylation K159 0.778 0.532 _MIYASSK(gl)DAIK_
CFL1 Ubiquitylation K182 -0.079 0.077 _HELQANCYEEVK(gl)DR_
FYN Ubiquitylation K13 0.286 _DKEATK(gl)LTEER_
FYN Phosphorylation S21 0.373 0.731 _DGS(ph)LNQSSGYR_
FYN Ubiquitylation K259 0.921 _LTDLSVK(gl)TK_
FYN Ubiquitylation K261 0.099 _LTDLSVKTK(gl)_
FYN Ubiquitylation K273 6.025 _SLCLEKK(gl)_
FYN Ubiquitylation K275 -0.521 _ESLQLIK(gl)R_
HSP90AA1 Ubiquitylation K69 0.820 -0.090 _YESLTDPSK(gl)LDSGK_
HSP90AA1 Ubiquitylation K74 0.543 _LDSGK(gl)ELHINLIPNKQDR_
HSP90AA1 Ubiquitylation K112 1.304 1.601 _ADLINNLGTIAK(gl)SGTK_
HSP90AA1 Ubiquitylation K185 0.963 _GTK(gl)VILHLK_
HSP90AA1 Ubiquitylation K208 1.745 _IKEIVK(gl)K_
HSP90AA1 Phosphorylation S231 2.338 0.649 _DKEVS(ph)DDEAEEK_
HSP90AA1 Phosphorylation S263 0.095 0.173 _ESEDKPEIEDVGS(ph)DEEEEKK_
HSP90AA1 Ubiquitylation K281 1.267 _IK(gl)EKYIDQEELNK_
HSP90AA1 Ubiquitylation K283 1.442 1.226 _EK(gl)YIDQEELNK_
HSP90AA1 Ubiquitylation K292 -0.237 0.506 _YIDQEELNK(gl)TKPIWTR_
HSP90AA1 Ubiquitylation K294 0.315 8.646 _TK(gl)PIWTR_
HSP90AA1 Ubiquitylation K362 0.969 0.946 _NNIK(gl)LYVR_
HSP90AA1 Ubiquitylation K407 0.827 1.121 _EMLQQSK(gl)ILK_
HSP90AA1 Ubiquitylation K443 0.820 0.951 _FYEQFSK(gl)NIK_
HSP90AA1 Ubiquitylation K446 0.314 1.126 _NIK(gl)LGIHEDSQNR_
HSP90AA1 Ubiquitylation K478 0.799 1.624 _YYTSASGDEM(ox)VSLK(gl)DYCTR_
HSP90AA1 Ubiquitylation K539 0.353 1.775 _EFEGK(gl)TLVSVTK_
HSP90AA1 Ubiquitylation K559 -0.316 _EGLELPEDEEEKK(gl)K_
HSP90AA1 Ubiquitylation K565 0.903 _K(gl)TKFENLCK_
HSP90AA1 Ubiquitylation K567 0.710 _TK(gl)FENLCK_
HSP90AA1 Ubiquitylation K576 0.874 _IMK(gl)DILEK_
HSP90AA1 Ubiquitylation K581 0.540 0.738 _DILEK(gl)KVEK_
HSP90AA1 Ubiquitylation K582 0.063 0.470 _K(gl)VEKVVVSNR_
HSP90AA1 Ubiquitylation K615 0.715 0.751 _IMK(gl)AQALR_
HSP90AA1 Ubiquitylation K631 0.361 0.974 _DNSTMGYMAAK(gl)K_
HSP90AB1 Ubiquitylation K64 0.829 -0.090 _YESLTDPSK(gl)LDSGKELK_
HSP90AB1 Ubiquitylation K69 0.661 0.380 _LDSGK(gl)ELK_
HSP90AB1 Ubiquitylation K72 -1.242 -0.130 _ELK(gl)IDIIPNPQER_
HSP90AB1 Phosphorylation S226 0.404 0.704 _EKEIS(ph)DDEAEEEK_
HSP90AB1 Phosphorylation S255 0.525 0.628 _IEDVGS(ph)DEEDDSGKDKK_
HSP90AB1 Phosphorylation S261 0.520 0.624 _IEDVGSDEEDDS(ph)GKDK_
HSP90AB1 Ubiquitylation K347 0.110 _RAPFDLFENK(gl)K_
HSP90AB1 Ubiquitylation K348 -0.096 _RAPFDLFENKK(gl)_
HSP90AB1 Ubiquitylation K428 0.308 _K(gl)FYEAFSK_
HSP90AB1 Ubiquitylation K435 0.847 0.933 _FYEAFSK(gl)NLK_
HSP90AB1 Ubiquitylation K438 1.021 -0.058 _NLK(gl)LGIHEDSTNR_
HSP90AB1 Ubiquitylation K481 0.811 _MKETQK(gl)SIYYITGESK_
HSP90AB1 Ubiquitylation K491 0.982 1.512 _SIYYITGESK(gl)EQVANSAFVER_
HSP90AB1 Ubiquitylation K531 0.745 1.350 _EFDGK(gl)SLVSVTK_
HSP90AB1 Ubiquitylation K559 0.847 1.549 _AK(gl)FENLCK_
HSP90AB1 Ubiquitylation K565 -0.066 _FENLCK(gl)LMK_
HSP90AB1 Ubiquitylation K573 0.243 0.360 _EILDK(gl)KVEK_
HSP90AB1 Ubiquitylation K574 0.241 0.550 _EILDKK(gl)VEK_
HSP90AB1 Ubiquitylation K623 0.520 1.081 _DNSTMGYM(ox)MAK(gl)K_
PAK1 Phosphorylation S174 -1.439 -0.597 _AVSETPAVPPVS(ph)EDEDDDDDDATPPPVIAPRPEHTK_
PAK1 Phosphorylation T212 0.312 _SVIEPLPVT(ph)PTR_
PAK1 Phosphorylation T219 -0.560 -0.962 _DVAT(ph)SPISPTENNTT(ph)PPDALTR_
PAK1 Phosphorylation S220 -0.916 -0.774 _DVATS(ph)PISPTENNTTPPDALTR_
PAK1 Phosphorylation S223 1.033 0.153 _DVATSPIS(ph)PTENNTTPPDALTR_
PAK1 Phosphorylation T225 -1.278 _DVATSPISPT(ph)ENNTTPPDALTR_
PAK1 Phosphorylation T230 -1.418 -1.502 _DVATSPISPTENNTT(ph)PPDALTR_
PAK2 Phosphorylation S2 -1.228 -0.902 _(ac)S(ph)DNGELEDKPPAPPVR_
PAK2 Ubiquitylation K136 1.213 _FYDSNTVK(gl)QK_
PAK2 Phosphorylation S141 -0.294 -0.321 _YLS(ph)FTPPEK_
PAK2 Ubiquitylation K370 -0.565 _DIK(gl)SDNVLLGMEGSVK_
PLXNA2 Ubiquitylation K1272 0.103 _ENDLTLK(gl)R_
PLXNA3 Ubiquitylation K622 2.255 _LQLLSK(gl)ETGVR_
PLXNA3 Ubiquitylation K1328 -1.042 -1.740 _ELDTPPNVEK(gl)ALR_
RAC1 Ubiquitylation K115 -1.745 -0.215 _AK(gl)WYPEVR_
RAC1 Ubiquitylation K142 0.492 _LDLRDDK(gl)DTIEK_
RAC1 Ubiquitylation K152 0.099 -0.292 _K(gl)LTPITYPQGLAMAK_
RAC1 Ubiquitylation K166 -0.981 -0.655 _LTPITYPQGLAMAK(gl)EIGAVK_
RAC1 Ubiquitylation K172 1.026 0.412 _EIGAVK(gl)YLECSALTQR_
RAC1 Ubiquitylation K185 -0.113 0.578 _GLK(gl)TVFDEAIR_
RAC1 Ubiquitylation K202 -1.379 -1.447 _AVLCPPPVK(gl)KR_
RAC1 Ubiquitylation K203 -1.708 -1.447 _AVLCPPPVKK(gl)_


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