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Query: PLXNA1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PLXNA1 0 0.567 0.330 0.040 -0.130 0.142 0.555

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for PLXNA1:


Pubmed-PLXNA1 »
Uniprot-PLXNA1 »
Biogrid-PLXNA1 »
ProteomicsDB-PLXNA1 »

Tumorportal-PLXNA1 »
COSMIC-PLXNA1 »
GenomeRNAi-PLXNA1 »
Genecards-PLXNA1


Protein-protein Interactions for PLXNA1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait DEFA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DEFA5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM19A4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MGAT4C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OS9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCGB1D1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ST8SIA4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM25 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PLXNA1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Rho_GTPase_activation_prot IPR008936 0.53
Category members Plexin_cytoplasmic_RasGAP_dom IPR013548 0.31
Category members IPT IPR002909 0.11
Category members Semap_dom IPR001627 0.04
Category members Plexin_repeat IPR002165 0
Category members Ig_E-set IPR014756 0
Category members Plexin-like_fold IPR016201 0


Protein complexes (CORUM database) featuring PLXNA1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5646 FARP2-NRP1-PlexinA1 complex Database 0.32
Category members Corum 5746 PlexinA1-NRP1-SEMA3A complex Database 0.32
Category members Corum 5745 PlexinA1-NRP1 complex Database 0.11
Category members Corum 5757 PLXNA1-RANBPM complex Database 0.11
Category members Corum 5689 SEMA6D-PlexinA1-NRP1 complex Database 0
Category members Corum 5762 CRMP-MICAL-PlexinA1 complex, induced by SEMA3A Database 0


Categories featuring PLXNA1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members Pathway Pathway_1147 REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION 0 1.89
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_673 REACTOME_AXON_GUIDANCE 0 1.06
Category members Pathway Pathway_674 REACTOME_SEMAPHORIN_INTERACTIONS 0 0.96
Category members Pathway Pathway_672 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION 0 0.88
Category members GO Category GO:0016020 membrane Database 0.52
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0007275 multicellular organismal development Database 0.31
Category members GO Category GO:0017154 semaphorin receptor activity Database 0.31
Category members GO Category GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching Database 0.27
Category members Pathway Pathway_1282 REACTOME_CRMPS_IN_SEMA3A_SIGNALING 0 0.17
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members GO Category GO:0002116 semaphorin receptor complex Database 0.05
Category members Pathway Pathway_1284 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS 0 0.04
Category members Pathway Pathway_1034 KEGG_AXON_GUIDANCE 0 0.04
Category members GO Category GO:0004872 receptor activity Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0014910 regulation of smooth muscle cell migration Database 0


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