Results for the Category
REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION
(Pathway_672)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| FARP2 | 2 | -0.210 | 0.300 | |||||
| FYN | 1 | 1.080 | -1.100 | |||||
| FYN | 1 | 1.080 | -1.100 | |||||
| PLXNA3 | 1 | -0.130 | 0.400 | |||||
| TLN1 | 1 | -0.130 | 0.000 | 0.807 | 0.246 | 0.137 | ||
| PLXNA2 | 0 | -1.160 | 1.870 | 0.107 | 0.180 | |||
| PLXNA2 | 0 | 1.880 | -0.800 | 0.107 | 0.180 | |||
| NRP1 | 0 | 0.880 | -0.670 | 0.909 | 0.353 | |||
| PLXNA1 | 0 | 0.330 | 0.040 | -0.130 | 0.142 | 0.555 | ||
| RAC1 | 0 | -0.580 | 1.580 | 0.486 | -0.364 | -0.568 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| FARP2 | Phosphorylation | T22 | -0.452 | _LGAQT(ph)PVGVSTLEPGQTLLPR_ | |
| FARP2 | Ubiquitylation | K385 | -0.011 | _ALTADLPK(gl)QSISFPEGLR_ | |
| FARP2 | Phosphorylation | T396 | -0.471 | _T(ph)PASPSSANAFYSLSPSTLVPSGLPEFK_ | |
| FARP2 | Phosphorylation | S425 | 1.871 | _DS(ph)SSSLTDPQVSYVK_ | |
| FARP2 | Phosphorylation | S426 | 0.595 | 0.624 | _DSS(ph)SSLTDPQVSYVK_ |
| FARP2 | Phosphorylation | S427 | 0.570 | _DSSS(ph)SLTDPQVSYVK_ | |
| FARP2 | Phosphorylation | S428 | 1.290 | 1.605 | _DSSSS(ph)LTDPQVSYVK_ |
| FARP2 | Phosphorylation | S439 | 0.020 | -0.277 | _DSSSSLTDPQVSYVKS(ph)PAAER_ |
| FYN | Ubiquitylation | K13 | 0.286 | _DKEATK(gl)LTEER_ | |
| FYN | Phosphorylation | S21 | 0.373 | 0.731 | _DGS(ph)LNQSSGYR_ |
| FYN | Ubiquitylation | K259 | 0.921 | _LTDLSVK(gl)TK_ | |
| FYN | Ubiquitylation | K261 | 0.099 | _LTDLSVKTK(gl)_ | |
| FYN | Ubiquitylation | K273 | 6.025 | _SLCLEKK(gl)_ | |
| FYN | Ubiquitylation | K275 | -0.521 | _ESLQLIK(gl)R_ | |
| PLXNA2 | Ubiquitylation | K1272 | 0.103 | _ENDLTLK(gl)R_ | |
| PLXNA3 | Ubiquitylation | K622 | 2.255 | _LQLLSK(gl)ETGVR_ | |
| PLXNA3 | Ubiquitylation | K1328 | -1.042 | -1.740 | _ELDTPPNVEK(gl)ALR_ |
| RAC1 | Ubiquitylation | K115 | -1.745 | -0.215 | _AK(gl)WYPEVR_ |
| RAC1 | Ubiquitylation | K142 | 0.492 | _LDLRDDK(gl)DTIEK_ | |
| RAC1 | Ubiquitylation | K152 | 0.099 | -0.292 | _K(gl)LTPITYPQGLAMAK_ |
| RAC1 | Ubiquitylation | K166 | -0.981 | -0.655 | _LTPITYPQGLAMAK(gl)EIGAVK_ |
| RAC1 | Ubiquitylation | K172 | 1.026 | 0.412 | _EIGAVK(gl)YLECSALTQR_ |
| RAC1 | Ubiquitylation | K185 | -0.113 | 0.578 | _GLK(gl)TVFDEAIR_ |
| RAC1 | Ubiquitylation | K202 | -1.379 | -1.447 | _AVLCPPPVK(gl)KR_ |
| RAC1 | Ubiquitylation | K203 | -1.708 | -1.447 | _AVLCPPPVKK(gl)_ |
| TLN1 | Ubiquitylation | K334 | -0.489 | 0.561 | _LLGITK(gl)ECVM(ox)R_ |
| TLN1 | Phosphorylation | S423 | 0.105 | _DHFGLEGDEESTMLEDS(ph)VSPKK_ | |
| TLN1 | Phosphorylation | S425 | -0.366 | -0.322 | _DHFGLEGDEESTMLEDSVS(ph)PKK_ |
| TLN1 | Ubiquitylation | K869 | -0.260 | _ILADATAK(gl)MVEAAK_ | |
| TLN1 | Ubiquitylation | K1541 | 0.365 | 2.311 | _EVANSTANLVK(gl)TIK_ |
| TLN1 | Ubiquitylation | K2021 | 0.309 | 0.479 | _EGILK(gl)TAK_ |
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