RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
W

Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
TOP1	3	0.970	-0.880
TOP1	3	0.970	-0.880	0.567	0.872	1.232	0.631	0.425
ERCC3	2	-1.110	1.490		2.619	2.418		0.499
TOP1MT	2	1.650	-0.670	0.567	0.872	1.232	0.631	0.425
HMGB1	2	-1.590	3.400		2.856	-1.899	0.030	-0.792
TOP2B	1	0.830	-0.650	-1.137			0.859	0.666
TOP2A	1	-1.940	3.540
TOP2A	1	-1.940	3.540	-1.993			0.211	0.211
TOP3A	1	2.070	-0.580				-0.370	0.720
TOP3A	1	2.070	-0.580		0.498	0.705
HMGB2	0	-0.350	0.170			-1.810	0.655	0.285

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
HMGB1	Ubiquitylation	K50	0.651		_WK(gl)TMSAK_
HMGB1	Ubiquitylation	K59	1.001	0.009	_GK(gl)FEDMAK_
HMGB1	Ubiquitylation	K114		0.314	_IK(gl)GEHPGLSIGDVAK_
HMGB1	Ubiquitylation	K127	0.018		_IKGEHPGLSIGDVAK(gl)K_
HMGB1	Ubiquitylation	K128	-0.407		_K(gl)LGEMWNNTAADDKQPYEK_
HMGB1	Ubiquitylation	K157	0.850		_YEK(gl)DIAAYR_
HMGB2	Ubiquitylation	K114	0.323		_IK(gl)SEHPGLSIGDTAK_
HMGB2	Ubiquitylation	K128	0.363		_K(gl)LGEMWSEQSAK_
HMGB2	Ubiquitylation	K147	0.205	-0.408	_DKQPYEQK(gl)AAK_
HMGB2	Ubiquitylation	K150	-0.251		_DKQPYEQKAAK(gl)_
TOP1	Phosphorylation	S10	0.973	1.937	_(ac)SGDHLHNDS(ph)QIEADFR_
TOP1	Ubiquitylation	K245	2.277		_FYYDGK(gl)VMK_
TOP1	Ubiquitylation	K252		1.900	_LSPK(gl)AEEVATFFAK_
TOP1	Ubiquitylation	K391	0.019		_DAK(gl)VPSPPPGHK_
TOP1	Ubiquitylation	K545	2.178		_YYNKVPVEK(gl)R_
TOP1	Ubiquitylation	K642	2.317		_TFEK(gl)SMMNLQTK_
TOP1MT	Ubiquitylation	K245	2.277		_FYYDGK(gl)VMK_
TOP1MT	Ubiquitylation	K252		1.900	_LSPK(gl)AEEVATFFAK_
TOP1MT	Ubiquitylation	K391	0.019		_DAK(gl)VPSPPPGHK_
TOP1MT	Ubiquitylation	K545	2.178		_YYNKVPVEK(gl)R_
TOP1MT	Ubiquitylation	K642	2.317		_TFEK(gl)SMMNLQTK_
TOP2A	Phosphorylation	S4	-0.623	-0.424	_(ac)M(ox)EVS(ph)PLQPVNENM(ox)QVNK_
TOP2A	Ubiquitylation	K17	-0.250		_(ac)MEVSPLQPVNENMQVNK(gl)IKK_
TOP2A	Ubiquitylation	K96		0.284	_IFDEILVNAADNK(gl)QR_
TOP2A	Ubiquitylation	K131	0.553	-0.638	_GIPVVEHK(gl)VEK_
TOP2A	Ubiquitylation	K386	-2.203		_ENMTLQPK(gl)SFGSTCQLSEK_
TOP2A	Ubiquitylation	K397	0.214	0.360	_SFGSTCQLSEK(gl)FIK_
TOP2A	Ubiquitylation	K426		-0.502	_AQVQLNKK(gl)_
TOP2A	Ubiquitylation	K489	-0.029	0.171	_GK(gl)ILNVR_
TOP2A	Ubiquitylation	K520		-0.260	_IVGLQYKK(gl)_
TOP2A	Ubiquitylation	K529	0.862	0.065	_NYEDEDSLK(gl)TLR_
TOP2A	Ubiquitylation	K614		-0.287	_YYK(gl)GLGTSTSK_
TOP2A	Ubiquitylation	K622		-0.581	_GLGTSTSK(gl)EAK_
TOP2A	Ubiquitylation	K632	-0.171	-0.248	_EYFADMK(gl)R_
TOP2A	Ubiquitylation	K655	-0.091	-0.407	_YSGPEDDAAISLAFSK(gl)K_
TOP2A	Ubiquitylation	K656	-0.091	-0.441	_YSGPEDDAAISLAFSKK(gl)_
TOP2A	Ubiquitylation	K723		-1.207	_SIPSMVDGLK(gl)PGQR_
TOP2A	Ubiquitylation	K1088		0.061	_GYDSDPVK(gl)AWK_
TOP2A	Phosphorylation	S1142	0.072	0.040	_VPDEEENEES(ph)DNEKETEK_
TOP2A	Ubiquitylation	K1159	-0.411	-0.659	_EQELDTLK(gl)R_
TOP2A	Ubiquitylation	K1199	-0.674	-1.759	_EKQDEQVGLPGKGGK(gl)_
TOP2A	Phosphorylation	S1249	-0.907	-0.546	_TQMAEVLPS(ph)PR_
TOP2A	Phosphorylation	S1283	0.168	0.028	_NENTEGS(ph)PQEDGVELEGLK_
TOP2A	Phosphorylation	S1411	0.232	-0.105	_S(ph)VVSDLEADDVK_
TOP2A	Phosphorylation	S1414	0.884	0.877	_SVVS(ph)DLEADDVK_
TOP2A	Phosphorylation	S1429	-1.415	-2.977	_GSVPLSS(ph)SPPATHFPDETEITNPVPK_
TOP2A	Phosphorylation	S1430		-1.317	_GSVPLSSS(ph)PPATHFPDETEITNPVPK_
TOP2A	Phosphorylation	T1434	-1.348		_GSVPLSSSPPAT(ph)HFPDETEITNPVPK_
TOP2A	Phosphorylation	S1506		-0.384	_RKPS(ph)TSDDSDSNFEK_
TOP2B	Ubiquitylation	K205		0.226	_FTVETACK(gl)EYK_
TOP2B	Ubiquitylation	K221		-0.165	_QTWMNNMMK(gl)TSEAK_
TOP2B	Ubiquitylation	K373		-0.347	_AGVSVK(gl)PFQVK_
TOP2B	Ubiquitylation	K412		-0.274	_SFGSK(gl)CQLSEK_
TOP2B	Ubiquitylation	K550		0.643	_SYDDAESLK(gl)TLR_
TOP2B	Ubiquitylation	K643		-0.133	_GLGTSTAK(gl)EAK_
TOP2B	Ubiquitylation	K646		0.051	_EAK(gl)EYFADMER_
TOP2B	Ubiquitylation	K676		-0.188	_YAGPEDDAAITLAFSK(gl)K_
TOP2B	Ubiquitylation	K677		-0.188	_YAGPEDDAAITLAFSK(gl)K_
TOP2B	Ubiquitylation	K1079		0.700	_FILEK(gl)IQGK_
TOP2B	Ubiquitylation	K1227		-0.462	_K(gl)LQLEETMPSPYGR_
TOP2B	Ubiquitylation	K1250		-0.673	_RIIPEITAM(ox)K(gl)ADASK_
TOP2B	Phosphorylation	S1400	-0.221	-0.192	_VKAS(ph)PITNDGEDEFVPSDGLDKDEYTFSPGK_
TOP2B	Phosphorylation	T1403	-0.017	-0.156	_VKASPIT(ph)NDGEDEFVPSDGLDKDEYTFSPGK_
TOP2B	Phosphorylation	S1413	-0.430	-0.661	_ASPITNDGEDEFVPS(ph)DGLDKDEYTFSPGK_
TOP2B	Phosphorylation	T1422	-0.362		_VKAS(ph)PITNDGEDEFVPSDGLDKDEYT(ph)FSPGK_
TOP2B	Phosphorylation	S1424	-1.672	-1.441	_ASPITNDGEDEFVPSDGLDKDEYTFS(ph)PGK_
TOP2B	Phosphorylation	S1454		1.291	_KSQDFGNLFSFPSYS(ph)QK_
TOP2B	Phosphorylation	S1466	-0.324	-0.202	_FDS(ph)NEEDSASVFSPSFGLK_
TOP2B	Phosphorylation	S1552	2.808		_ASGS(ph)ENEGDYNPGRK_
TOP2B	Phosphorylation	S1581	-0.797	-1.005	_KTSFDQDS(ph)DVDIFPSDFPTEPPSLPR_