Results for the Category
negative regulation of interleukin-6 production
(GO:0032715)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| ARRB2 | 1 | 2.000 | -1.160 | -0.340 | 0.096 | 0.051 | -1.604 | |
| GBA | 1 | -1.380 | 2.580 | 0.407 | 0.357 | 0.150 | ||
| TNFRSF1A | 0 | -0.590 | 0.470 | |||||
| CSK | 0 | 1.200 | -0.960 | -1.211 | ||||
| CSK | 0 | 1.200 | -0.960 | |||||
| TNFAIP3 | 0 | 0.760 | -0.500 | |||||
| VIMP | 0 | 0.490 | -0.510 | -2.036 | ||||
| ARRB1 | 0 | 0.960 | -0.620 | |||||
| NLRX1 | 0 | -0.720 | 0.810 | -0.012 | ||||
| GAS6 | 0 | 0.020 | 0.220 | -1.517 | -0.502 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| ARRB1 | Phosphorylation | S412 | 0.138 | 0.253 | _GMKDDKEEEEDGTGS(ph)PQLNNR_ |
| ARRB2 | Ubiquitylation | K199 | -1.933 | _VQFAPEK(gl)PGPQPSAETTR_ | |
| CSK | Ubiquitylation | K196 | -0.133 | _SGWALNMKELK(gl)_ | |
| TNFAIP3 | Ubiquitylation | K722 | 0.496 | 0.176 | _ASCK(gl)NILACR_ |
| TNFRSF1A | Ubiquitylation | K242 | -0.111 | _SK(gl)LYSIVCGK_ | |
| VIMP | Ubiquitylation | K117 | -2.952 | -1.705 | _AAAAVEPDVVVK(gl)R_ |
| VIMP | Ubiquitylation | K190 | -1.565 | -1.157 | _KPQEEDSPGPSTSSVLK(gl)R_ |
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