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Results for the Category
Familial isolated arrhythmogenic ventricular dysplasia biventricular form
(Familial_isolated_arrhythmogenic_ventricular_dysplasia_biventricular_form)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
TTN 1 2.130 -1.190 0.133 0.277 0.244 0.213
LMNA 1 0.760 -0.400 1.025 -0.121 0.091 1.281 0.818
DSG2 0 0.200 0.000 0.827 -0.456 -0.256
PKP2 0 0.120 0.970 0.814 0.742
PKP2 0 0.120 0.970
DSP 0 -0.660 1.420 -2.938 -0.696 -0.240
TGFB3 0 0.900 -0.540
DSC2 0 0.080 -0.120
TMEM43 0 0.040 -0.250 0.499 0.600
CTNNA3 0 -0.010 -0.400 0.139 0.436 0.323

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
DSC2 Ubiquitylation K913 -0.807 _TLAEACMK(gl)R_
DSG2 Phosphorylation S680 -0.220 -0.071 _VVPSFLPVDQGGS(ph)LVGR_
DSG2 Ubiquitylation K692 0.377 _NGVGGMAK(gl)EATMK_
DSG2 Ubiquitylation K697 0.688 0.914 _EATMK(gl)GSSSASIVK_
DSG2 Ubiquitylation K706 0.722 _GSSSASIVK(gl)GQHEMSEMDGR_
DSG2 Ubiquitylation K746 1.168 1.231 _ATQFTGATGAIM(ox)TTETTK(gl)TAR_
DSG2 Phosphorylation S782 0.571 _AAS(ph)YTEEDENHTAK_
DSP Phosphorylation S22 0.083 -0.070 _AES(ph)GPDLR_
DSP Ubiquitylation K94 0.120 _AELIVQPELK(gl)YGDGIQLTR_
DSP Ubiquitylation K140 0.440 0.037 _QMGQPCDAYQK(gl)R_
DSP Ubiquitylation K154 0.266 -0.098 _ALYK(gl)AISVPR_
DSP Phosphorylation S176 0.188 _GGGGYTCQS(ph)GSGWDEFTK_
DSP Ubiquitylation K239 -0.069 _WQLDKIK(gl)_
DSP Ubiquitylation K322 1.259 _MSQLEVK(gl)EK_
DSP Ubiquitylation K324 1.259 _MSQLEVK(gl)EK_
DSP Ubiquitylation K1028 1.475 _SLEDLK(gl)LK_
DSP Ubiquitylation K1802 0.287 1.314 _IQESK(gl)NQCTQVVQER_
DSP Phosphorylation S2209 0.704 1.055 _SMS(ph)FQGIR_
DSP Phosphorylation S2606 -0.052 -0.018 _S(ph)SSFSDTLEESSPIAAIFDTENLEK_
DSP Phosphorylation S2608 0.063 0.167 _SSS(ph)FSDTLEESSPIAAIFDTENLEK_
DSP Phosphorylation S2632 1.154 _SSSFSDTLEESS(ph)PIAAIFDTENLEKIS(ph)ITEGIERGIVDSITGQR_
DSP Ubiquitylation K2811 -0.793 _LLEAASVSSK(gl)GLPSPYNMSSAPGSR_
DSP Phosphorylation S2815 -1.038 -0.597 _GLPS(ph)PYNMSSAPGSR_
DSP Phosphorylation S2820 -0.905 -0.967 _GLPSPYNMS(ph)SAPGSR_
DSP Phosphorylation S2821 -0.690 -0.873 _GLPSPYNMSS(ph)APGSR_
DSP Phosphorylation S2825 -1.381 -0.714 _GLPSPYNM(ox)SSAPGS(ph)R_
LMNA Phosphorylation T19 -1.262 _SGAQASST(ph)PLS(ph)PTR_
LMNA Phosphorylation S22 -0.433 0.377 _SGAQASST(ph)PLS(ph)PTR_
LMNA Ubiquitylation K32 0.054 _LQEK(gl)EDLQELNDR_
LMNA Ubiquitylation K78 -0.306 _EVSGIK(gl)AAYEAELGDAR_
LMNA Ubiquitylation K97 0.499 -0.167 _TLDSVAK(gl)ER_
LMNA Ubiquitylation K108 0.586 _LQLELSK(gl)VR_
LMNA Ubiquitylation K114 0.753 _VREEFK(gl)ELK_
LMNA Ubiquitylation K117 0.571 _VREEFKELK(gl)AR_
LMNA Ubiquitylation K122 0.401 _NTK(gl)KEGDLIAAQAR_
LMNA Ubiquitylation K123 0.401 _NTK(gl)KEGDLIAAQAR_
LMNA Ubiquitylation K135 0.856 1.129 _LK(gl)DLEALLNSK_
LMNA Ubiquitylation K155 -0.218 0.375 _EAALSTALSEK(gl)R_
LMNA Ubiquitylation K171 0.656 0.450 _GQVAK(gl)LEAALGEAKK_
LMNA Ubiquitylation K180 0.977 0.753 _LEAALGEAK(gl)K_
LMNA Ubiquitylation K181 0.458 0.679 _K(gl)QLQDEMLR_
LMNA Ubiquitylation K219 0.784 0.456 _NIYSEELRETK(gl)R_
LMNA Ubiquitylation K233 0.194 1.930 _LVEIDNGK(gl)QREFESR_
LMNA Ubiquitylation K261 0.576 _AQHEDQVEQYKK(gl)ELEK_
LMNA Ubiquitylation K265 0.532 0.714 _ELEK(gl)TYSAK_
LMNA Ubiquitylation K270 0.362 0.777 _TYSAK(gl)LDNAR_
LMNA Ubiquitylation K311 0.853 0.977 _IDSLSAQLSQLQK(gl)QLAAK_
LMNA Ubiquitylation K378 -0.030 0.701 _K(gl)LLEGEEER_
LMNA Phosphorylation S390 -0.020 -0.112 _LRLS(ph)PSPTSQR_
LMNA Phosphorylation S392 -0.062 -0.026 _LSPS(ph)PTSQR_
LMNA Phosphorylation S403 0.641 _GRAS(ph)SHSSQTQGGGSVTK_
LMNA Phosphorylation S458 0.520 _NKS(ph)NEDQSMGNWQIK_
LMNA Phosphorylation S632 0.730 _SVGGS(ph)GGGSFGDNLVTR_
LMNA Phosphorylation S636 0.537 1.498 _SVGGSGGGS(ph)FGDNLVTR_
PKP2 Phosphorylation S82 0.172 0.473 _TSS(ph)VPEYVYNLHLVENDFVGGR_
PKP2 Ubiquitylation K134 0.755 -0.110 _GTAQYSSQK(gl)SVEER_
PKP2 Phosphorylation S135 0.873 0.521 _GTAQYSSQKS(ph)VEER_
PKP2 Phosphorylation S151 0.440 0.323 _RLEIS(ph)PDSSPER_
PKP2 Phosphorylation S154 0.267 0.205 _LEISPDS(ph)SPER_
PKP2 Phosphorylation S155 -0.249 0.172 _RLEISPDSS(ph)PER_
PKP2 Phosphorylation S329 0.351 0.264 _AHLTVGQAAAGGS(ph)GNLLTER_
PKP2 Ubiquitylation K643 1.209 0.678 _NIQTDNNK(gl)SIGCFGSR_
TGFB3 Ubiquitylation K50 -0.557 _GQILSK(gl)LR_
TMEM43 Ubiquitylation K159 -0.120 _SEIINSK(gl)NFDR_
TMEM43 Ubiquitylation K307 0.935 _SNSMK(gl)TWGLR_
TTN Ubiquitylation K27327 -0.283 0.183 _AGEVLK(gl)INADIAGR_


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