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Query: TMEM43

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TMEM43 0 2.034 0.040 -0.250 0.499 0.600

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TMEM43 Ubiquitylation K307 0.935 _SNSMK(gl)TWGLR_
TMEM43 Ubiquitylation K159 -0.120 _SEIINSK(gl)NFDR_

Background Information for TMEM43:


Pubmed-TMEM43 »
Uniprot-TMEM43 »
Biogrid-TMEM43 »
ProteomicsDB-TMEM43 »

Tumorportal-TMEM43 »
COSMIC-TMEM43 »
GenomeRNAi-TMEM43 »
Genecards-TMEM43


Protein-protein Interactions for TMEM43
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BMPR1A Cat. description Hein, Mann, Cell 2015
Category members IP bait C1QBP Cat. description Hein, Mann, Cell 2015
Category members IP bait GOLT1B Cat. description Hein, Mann, Cell 2015
Category members IP bait KTN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MMGT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB11A Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB5C Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB7A Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMEM109 Cat. description Hein, Mann, Cell 2015
Category members IP bait TNPO1 Cat. description Hein, Mann, Cell 2015
Category members IP bait VAPA Cat. description Hein, Mann, Cell 2015
Category members IP bait APOA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BZW1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BZW2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPP6R2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RTN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RTN4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPPL2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TBRG4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM43 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YIPF3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TMEM43
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring TMEM43
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TMEM43
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005637 nuclear inner membrane Database 1.98
Category members Disease phenotype Autosomal_dominant_Emery-Dreifuss_muscular_dystrophy Autosomal dominant Emery-Dreifuss muscular dystrophy Database 0.89
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members Disease phenotype Familial_isolated_arrhythmogenic_ventricular_dysplasia_biventricular_form Familial isolated arrhythmogenic ventricular dysplasia biventricular form Database 0.05
Category members Disease phenotype Familial_isolated_arrhythmogenic_ventricular_dysplasia_left_dominant_form Familial isolated arrhythmogenic ventricular dysplasia left dominant form Database 0.05
Category members Disease phenotype Familial_isolated_arrhythmogenic_ventricular_dysplasia_right_dominant_form Familial isolated arrhythmogenic ventricular dysplasia right dominant form Database 0.05


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