Results for the Category
Autosomal dominant Emery-Dreifuss muscular dystrophy
(Autosomal_dominant_Emery-Dreifuss_muscular_dystrophy)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| SYNE2 | 1 | -2.100 | 3.290 | 0.830 | 0.623 | |||
| LMNA | 1 | 0.760 | -0.400 | 1.025 | -0.121 | 0.091 | 1.281 | 0.818 |
| SYNE1 | 0 | -0.990 | 2.410 | 0.468 | ||||
| TMEM43 | 0 | 0.040 | -0.250 | 0.499 | 0.600 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| LMNA | Phosphorylation | T19 | -1.262 | _SGAQASST(ph)PLS(ph)PTR_ | |
| LMNA | Phosphorylation | S22 | -0.433 | 0.377 | _SGAQASST(ph)PLS(ph)PTR_ |
| LMNA | Ubiquitylation | K32 | 0.054 | _LQEK(gl)EDLQELNDR_ | |
| LMNA | Ubiquitylation | K78 | -0.306 | _EVSGIK(gl)AAYEAELGDAR_ | |
| LMNA | Ubiquitylation | K97 | 0.499 | -0.167 | _TLDSVAK(gl)ER_ |
| LMNA | Ubiquitylation | K108 | 0.586 | _LQLELSK(gl)VR_ | |
| LMNA | Ubiquitylation | K114 | 0.753 | _VREEFK(gl)ELK_ | |
| LMNA | Ubiquitylation | K117 | 0.571 | _VREEFKELK(gl)AR_ | |
| LMNA | Ubiquitylation | K122 | 0.401 | _NTK(gl)KEGDLIAAQAR_ | |
| LMNA | Ubiquitylation | K123 | 0.401 | _NTK(gl)KEGDLIAAQAR_ | |
| LMNA | Ubiquitylation | K135 | 0.856 | 1.129 | _LK(gl)DLEALLNSK_ |
| LMNA | Ubiquitylation | K155 | -0.218 | 0.375 | _EAALSTALSEK(gl)R_ |
| LMNA | Ubiquitylation | K171 | 0.656 | 0.450 | _GQVAK(gl)LEAALGEAKK_ |
| LMNA | Ubiquitylation | K180 | 0.977 | 0.753 | _LEAALGEAK(gl)K_ |
| LMNA | Ubiquitylation | K181 | 0.458 | 0.679 | _K(gl)QLQDEMLR_ |
| LMNA | Ubiquitylation | K219 | 0.784 | 0.456 | _NIYSEELRETK(gl)R_ |
| LMNA | Ubiquitylation | K233 | 0.194 | 1.930 | _LVEIDNGK(gl)QREFESR_ |
| LMNA | Ubiquitylation | K261 | 0.576 | _AQHEDQVEQYKK(gl)ELEK_ | |
| LMNA | Ubiquitylation | K265 | 0.532 | 0.714 | _ELEK(gl)TYSAK_ |
| LMNA | Ubiquitylation | K270 | 0.362 | 0.777 | _TYSAK(gl)LDNAR_ |
| LMNA | Ubiquitylation | K311 | 0.853 | 0.977 | _IDSLSAQLSQLQK(gl)QLAAK_ |
| LMNA | Ubiquitylation | K378 | -0.030 | 0.701 | _K(gl)LLEGEEER_ |
| LMNA | Phosphorylation | S390 | -0.020 | -0.112 | _LRLS(ph)PSPTSQR_ |
| LMNA | Phosphorylation | S392 | -0.062 | -0.026 | _LSPS(ph)PTSQR_ |
| LMNA | Phosphorylation | S403 | 0.641 | _GRAS(ph)SHSSQTQGGGSVTK_ | |
| LMNA | Phosphorylation | S458 | 0.520 | _NKS(ph)NEDQSMGNWQIK_ | |
| LMNA | Phosphorylation | S632 | 0.730 | _SVGGS(ph)GGGSFGDNLVTR_ | |
| LMNA | Phosphorylation | S636 | 0.537 | 1.498 | _SVGGSGGGS(ph)FGDNLVTR_ |
| SYNE1 | Phosphorylation | S8305 | 0.804 | 0.456 | _ALPS(ph)EDEEGQDDKDFYLR_ |
| SYNE1 | Phosphorylation | T8360 | 0.406 | 0.397 | _SKT(ph)PTGPELDTSYK_ |
| SYNE2 | Phosphorylation | S4108 | 1.388 | _RGS(ph)MSYLAAVEEEVEESSVK_ | |
| SYNE2 | Phosphorylation | S6361 | -0.215 | -0.097 | _LTSCTPGLEDEKEAS(ph)ENETDMEDPR_ |
| SYNE2 | Phosphorylation | T6365 | 0.448 | _LTSCTPGLEDEKEASENET(ph)DMEDPR_ | |
| TMEM43 | Ubiquitylation | K159 | -0.120 | _SEIINSK(gl)NFDR_ | |
| TMEM43 | Ubiquitylation | K307 | 0.935 | _SNSMK(gl)TWGLR_ |
.
© Copyright Svejstrup Laboratory 2015