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Query: TTC8

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TTC8 0 0.324 0.800 -1.070

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TTC8 Ubiquitylation K259 0.324 _VQIGK(gl)CYYR_
TTC8 Ubiquitylation K184 -0.765 _LNLTK(gl)YSQKPK_

Background Information for TTC8:


Pubmed-TTC8 »
Uniprot-TTC8 »
Biogrid-TTC8 »
ProteomicsDB-TTC8 »

Tumorportal-TTC8 »
COSMIC-TTC8 »
GenomeRNAi-TTC8 »
Genecards-TTC8


Protein-protein Interactions for TTC8
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BBS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BBS5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BBS7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDC16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LZTFL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NME3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TTC8
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members TPR_1 IPR001440 1.39
Category members TPR-contain_dom IPR013026 0.97
Category members TPR_repeat IPR019734 0.93


Protein complexes (CORUM database) featuring TTC8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TTC8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0005813 centrosome Database 0.75
Category members GO Category GO:0001103 RNA polymerase II repressing transcription factor binding Database 0.36
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members GO Category GO:0034464 BBSome Database 0.1
Category members GO Category GO:0021772 olfactory bulb development Database 0.06
Category members GO Category GO:0035264 multicellular organism growth Database 0.04
Category members Disease phenotype BARDET-BIEDL_SYNDROME BARDET-BIEDL SYNDROME Database 0
Category members Disease phenotype Retinitis_pigmentosa Retinitis pigmentosa Database 0
Category members GO Category GO:0005929 cilium Database 0
Category members GO Category GO:0005932 microtubule basal body Database 0
Category members GO Category GO:0007608 sensory perception of smell Database 0
Category members GO Category GO:0032391 photoreceptor connecting cilium Database 0
Category members GO Category GO:0032880 regulation of protein localization Database 0
Category members GO Category GO:0042384 cilium assembly Database 0
Category members GO Category GO:0045444 fat cell differentiation Database 0
Category members GO Category GO:0060170 ciliary membrane Database 0


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