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Query: TMF1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TMF1 0 1.009 1.240 -1.110 0.028 0.252

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TMF1 Phosphorylation S344 0.779 -0.050 _SVSEINS(ph)DDELSGK_
TMF1 Phosphorylation S399 -0.276 -0.307 _S(ph)ATPVNCEQPDILVSSTPINEGQTVLDK_
TMF1 Phosphorylation T401 -0.276 -0.307 _S(ph)ATPVNCEQPDILVSSTPINEGQTVLDK_
TMF1 Phosphorylation S160 -1.216 _DSSLCVS(ph)GETLAAGTSSPK_

Background Information for TMF1:


Pubmed-TMF1 »
Uniprot-TMF1 »
Biogrid-TMF1 »
ProteomicsDB-TMF1 »

Tumorportal-TMF1 »
COSMIC-TMF1 »
GenomeRNAi-TMF1 »
Genecards-TMF1


Protein-protein Interactions for TMF1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait USP7 Cat. description Hein, Mann, Cell 2015
Category members IP bait AP1M2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BSPRY Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA1984 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLK1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCP10L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TMF1
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring TMF1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TMF1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members Pathway Pathway_880 PID_AR_PATHWAY 0 0.58
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0003712 transcription cofactor activity Database 0.21
Category members GO Category GO:0007289 spermatid nucleus differentiation Database 0.18
Category members GO Category GO:0042742 defense response to bacterium Database 0.06
Category members GO Category GO:0001819 positive regulation of cytokine production Database 0.05
Category members GO Category GO:0001675 acrosome assembly Database 0.02
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007286 spermatid development Database 0
Category members GO Category GO:0008584 male gonad development Database 0
Category members GO Category GO:0010629 negative regulation of gene expression Database 0
Category members GO Category GO:0030317 sperm motility Database 0
Category members GO Category GO:0032275 luteinizing hormone secretion Database 0
Category members GO Category GO:0033327 Leydig cell differentiation Database 0
Category members GO Category GO:0061136 regulation of proteasomal protein catabolic process Database 0
Category members GO Category GO:0071407 cellular response to organic cyclic compound Database 0


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