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Query: TIMELESS

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TIMELESS 2 5.672 -0.820 1.340 -0.115 -0.810 1.489 0.880 0.424

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TIMELESS Phosphorylation S1149 1.556 1.776 _KAGLAS(ph)PEEEDAVGKEPLK_
TIMELESS Phosphorylation S1173 0.502 _RQLLDS(ph)DEEQEEDEGR_
TIMELESS Phosphorylation S1087 0.076 -0.254 _LS(ph)PTQLR_
TIMELESS Ubiquitylation K528 -0.868 _GNLVVQNK(gl)QK_
TIMELESS Ubiquitylation K530 -0.868 _GNLVVQNK(gl)QK_

Background Information for TIMELESS:


Pubmed-TIMELESS »
Uniprot-TIMELESS »
Biogrid-TIMELESS »
ProteomicsDB-TIMELESS »

Tumorportal-TIMELESS »
COSMIC-TIMELESS »
GenomeRNAi-TIMELESS »
Genecards-TIMELESS


Protein-protein Interactions for TIMELESS
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CLSPN Cat. description Hein, Mann, Cell 2015
Category members IP bait TBC1D16 Cat. description Hein, Mann, Cell 2015
Category members IP bait TIMELESS Cat. description Hein, Mann, Cell 2015
Category members IP bait TIPIN Cat. description Hein, Mann, Cell 2015
Category members IP bait CD70 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CSGALNACT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FCGRT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GINS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait H2AFX Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MCM3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MCM7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SSRP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TIPIN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VSIG1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TIMELESS
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring TIMELESS
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TIMELESS
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0006974 cellular response to DNA damage stimulus Database 3.57
Category members Pathway Pathway_865 PID_ATR_PATHWAY 0 3.46
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0000790 nuclear chromatin Database 0.46
Category members GO Category GO:0030324 lung development Database 0.39
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0009628 response to abiotic stimulus Database 0.1
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members Pathway Pathway_1249 PID_CIRCADIAN_PATHWAY 0 0
Category members GO Category GO:0002009 morphogenesis of an epithelium Database 0
Category members GO Category GO:0007623 circadian rhythm Database 0
Category members GO Category GO:0009582 detection of abiotic stimulus Database 0
Category members GO Category GO:0009790 embryo development Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0044770 cell cycle phase transition Database 0
Category members GO Category GO:0048754 branching morphogenesis of an epithelial tube Database 0


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