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Query: SOX6

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SOX6 0 -1.009 1.430 -0.800

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SOX6 Phosphorylation S98 -0.827 -0.182 _NTSTS(ph)PHKPDEGSR_

Background Information for SOX6:


Pubmed-SOX6 »
Uniprot-SOX6 »
Biogrid-SOX6 »
ProteomicsDB-SOX6 »

Tumorportal-SOX6 »
COSMIC-SOX6 »
GenomeRNAi-SOX6 »
Genecards-SOX6


Protein-protein Interactions for SOX6
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SOX5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SOX6
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members HMG_box_dom IPR009071 0.31


Protein complexes (CORUM database) featuring SOX6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SOX6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0001701 in utero embryonic development Database 0.2
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members GO Category GO:0030218 erythrocyte differentiation Database 0.13
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0042692 muscle cell differentiation Database 0.1
Category members GO Category GO:0048708 astrocyte differentiation Database 0.04
Category members GO Category GO:0016458 gene silencing Database 0.03
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0044212 transcription regulatory region DNA binding Database 0
Category members GO Category GO:0000902 cell morphogenesis Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007517 muscle organ development Database 0
Category members GO Category GO:0009791 post-embryonic development Database 0
Category members GO Category GO:0010468 regulation of gene expression Database 0
Category members GO Category GO:0021778 oligodendrocyte cell fate specification Database 0
Category members GO Category GO:0030097 hemopoiesis Database 0
Category members GO Category GO:0032332 positive regulation of chondrocyte differentiation Database 0
Category members GO Category GO:0035051 cardiocyte differentiation Database 0
Category members GO Category GO:0045165 cell fate commitment Database 0
Category members GO Category GO:0048709 oligodendrocyte differentiation Database 0
Category members GO Category GO:0048821 erythrocyte development Database 0
Category members GO Category GO:0051216 cartilage development Database 0
Category members GO Category GO:0061036 positive regulation of cartilage development Database 0


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