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Query: RBBP7

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RBBP7 0 5.647 -0.080 -0.020
RBBP7 0 5.647 -0.080 -0.020 0.397 0.000 0.776
RBBP7 0 5.647 -0.080 -0.020 0.602 0.336 0.890 0.363 0.402

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RBBP7 Phosphorylation S3 1.036 1.447 _(ac)AS(ph)KEMFEDTVEER_
RBBP7 Phosphorylation S145 0.319 1.248 _TPS(ph)SDVLVFDYTK_
RBBP7 Ubiquitylation K236 0.469 _DSSVK(gl)LYQTR_
RBBP7 Ubiquitylation K21 0.081 -0.004 _VINEEYK(gl)IWK_
RBBP7 Ubiquitylation K214 -0.021 _EGK(gl)IVDAK_
RBBP7 Ubiquitylation K4 0.122 -0.804 _(ac)ASK(gl)EMFEDTVEER_
RBBP7 Ubiquitylation K159 -1.249 -3.808 _HPAK(gl)PDPSGECNPDLR_

Background Information for RBBP7:





Protein-protein Interactions for RBBP7

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ASF1A Cat. description Hein, Mann, Cell 2015
Category members IP bait C1QBP Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK2AP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CHAF1A Cat. description Hein, Mann, Cell 2015
Category members IP bait EED Cat. description Hein, Mann, Cell 2015
Category members IP bait EZH2 Cat. description Hein, Mann, Cell 2015
Category members IP bait FAM60A Cat. description Hein, Mann, Cell 2015
Category members IP bait GATAD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HDAC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HMG20A Cat. description Hein, Mann, Cell 2015
Category members IP bait MAX Cat. description Hein, Mann, Cell 2015
Category members IP bait MBD2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MTA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MTA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait NASP Cat. description Hein, Mann, Cell 2015
Category members IP bait NLRP3 Cat. description Hein, Mann, Cell 2015
Category members IP bait PHF12 Cat. description Hein, Mann, Cell 2015
Category members IP bait SAP30 Cat. description Hein, Mann, Cell 2015
Category members IP bait SIN3A Cat. description Hein, Mann, Cell 2015
Category members IP bait SIN3B Cat. description Hein, Mann, Cell 2015
Category members IP bait TCF20 Cat. description Hein, Mann, Cell 2015
Category members IP bait ZMYND8 Cat. description Hein, Mann, Cell 2015
Category members IP bait AEBP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ASF1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BRMS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM60A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GATAD2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HAT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H4A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ING2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MBD3L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MORF4L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MTA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PHF20L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBBP7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF219 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RBBP7

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members WD40_repeat IPR001680 0.52
Category members Histone-bd_RBBP4_N IPR022052 0.49
Category members G-protein_beta_WD-40_rep IPR020472 0.12


Protein complexes (CORUM database) featuring RBBP7

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 282 SNF2h-cohesin-NuRD complex Database 6.11
Category members Corum 1257 ALL-1 supercomplex Database 4.3
Category members Corum 739 SIN3-ING1b complex II Database 4.24
Category members Corum 659 MeCP1 complex Database 4.17
Category members Corum 685 MeCP1 complex Database 4.17
Category members Corum 62 MeCP1 complex Database 3.53
Category members Corum 646 HDAC1-associated protein complex Database 3.34
Category members Corum 649 HDAC1-associated core complex cII Database 3.34
Category members Corum 61 Mi2/NuRD complex Database 2.87
Category members Corum 650 HDAC2-asscociated core complex Database 2.26
Category members Corum 888 MTA2 complex Database 2.24
Category members Corum 632 Anti-HDAC2 complex Database 2.11
Category members Corum 2721 HCF-1 complex Database 2.08
Category members Corum 3048 mSin3A complex Database 1.84
Category members Corum 691 SIN3-SAP25 complex Database 1.77
Category members Corum 743 SIN3-SAP25 complex Database 1.77
Category members Corum 591 SAP complex (Sin3-associated protein complex) Database 1.75
Category members Corum 886 MTA1 complex Database 1.68
Category members Corum 283 Sin3 complex Database 1.47
Category members Corum 54 SIN3 complex Database 1.47
Category members Corum 732 SIN3 complex Database 1.47
Category members Corum 738 SIN3-ING1b complex I Database 1.47
Category members Corum 100 hNURF complex Database 1.44
Category members Corum 919 hNURF complex Database 1.44
Category members Corum 596 SIN3-HDAC-SAP30-ARID4 complex Database 1.42
Category members Corum 695 SIN3-HDAC-SAP30-ARID4 complex Database 1.42
Category members Corum 698 SIN3-HDAC-SAP30-ARID4 complex Database 1.42
Category members Corum 889 MTA1-HDAC core complex Database 1.41
Category members Corum 592 SAP complex (Sin3-associated protein complex) Database 1.33
Category members Corum 2851 ING2 complex Database 0.74
Category members Corum 696 BRMS1-SIN3-HDAC complex Database 0.66
Category members Corum 105 Polycomb repressive complex 2 (PRC 2) Database 0.57
Category members Corum 995 Polycomb repressive complex 3 (PRC3) Database 0.57
Category members Corum 996 Polycomb repressive complex 2 (PRC2) Database 0.57


Categories featuring RBBP7

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members Pathway Pathway_319 REACTOME_CHROMOSOME_MAINTENANCE 0 7.37
Category members GO Category GO:0034080 CENP-A containing nucleosome assembly at centromere Database 4.75
Category members Pathway Pathway_1281 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE 0 4.19
Category members GO Category GO:0006334 nucleosome assembly Database 3.77
Category members GO Category GO:0006260 DNA replication Database 3.34
Category members Pathway Pathway_881 PID_TELOMERASE_PATHWAY 0 2.64
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0016581 NuRD complex Database 1.15
Category members Pathway Pathway_943 PID_HDAC_CLASSI_PATHWAY 0 1.08
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0035098 ESC/E(Z) complex Database 0.47
Category members Pathway Pathway_845 PID_SMAD2_3NUCLEAR_PATHWAY 0 0.46
Category members GO Category GO:0007275 multicellular organismal development Database 0.31
Category members GO Category GO:0030308 negative regulation of cell growth Database 0.18
Category members Pathway Pathway_984 PID_HEDGEHOG_GLI_PATHWAY 0 0.1
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02


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