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Query: RAB8B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RAB8B 0 1.549 -0.070 0.130 -0.216
RAB8B 0 1.549 -0.070 0.130 1.641 -1.484 0.560 0.491
RAB8B 0 1.549 -0.070 0.130 -0.051 0.529 0.549

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RAB8B Ubiquitylation K213 -0.059 0.420 _DILLK(gl)SGGR_
RAB8B Ubiquitylation K163 0.199 _LLLGNK(gl)CDMEAK_
RAB8B Ubiquitylation K102 -0.105 _SFENISK(gl)WLR_
RAB8B Ubiquitylation K174 -0.188 _VQK(gl)EQADKLAR_

Background Information for RAB8B:


Pubmed-RAB8B »
Uniprot-RAB8B »
Biogrid-RAB8B »
ProteomicsDB-RAB8B »

Tumorportal-RAB8B »
COSMIC-RAB8B »
GenomeRNAi-RAB8B »
Genecards-RAB8B


Protein-protein Interactions for RAB8B
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CUL3 Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB8B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPH3A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RAB8B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members EF_GTP-bd_dom IPR000795 1.57
Category members Ran_GTPase IPR002041 1.25
Category members Small_GTPase_ARF/SAR IPR006689 0.8
Category members Small_GTPase_Ras IPR020849 0.7
Category members Small_GTPase_Rho IPR003578 0.65
Category members Small_GTPase IPR001806 0.65
Category members Gtr1_RagA IPR006762 0.63
Category members Small_GTPase_Rab_type IPR003579 0.51
Category members MIRO-like IPR013684 0.4
Category members Small_GTP-bd_dom IPR005225 0.32
Category members SRP_receptor_beta_su IPR019009 0.13
Category members Small_GTPase_ARF IPR024156 0


Protein complexes (CORUM database) featuring RAB8B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RAB8B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0006913 nucleocytoplasmic transport Database 2.96
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0030670 phagocytic vesicle membrane Database 0.37
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0006184 GTP catabolic process Database 0.29
Category members GO Category GO:0030911 TPR domain binding Database 0.27
Category members GO Category GO:0019003 GDP binding Database 0.18
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members GO Category GO:0045335 phagocytic vesicle Database 0.16
Category members GO Category GO:0005778 peroxisomal membrane Database 0.01
Category members GO Category GO:0005102 receptor binding Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0031346 positive regulation of cell projection organization Database 0
Category members GO Category GO:0031410 cytoplasmic vesicle Database 0
Category members GO Category GO:0034332 adherens junction organization Database 0
Category members GO Category GO:0045046 protein import into peroxisome membrane Database 0
Category members GO Category GO:0051286 cell tip Database 0
Category members GO Category GO:0051461 positive regulation of corticotropin secretion Database 0


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