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Query: PPAP2B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PPAP2B 0 2.106 -0.750 0.840

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PPAP2B Ubiquitylation K8 0.265 0.647 _YDK(gl)AIVPESK_
PPAP2B Ubiquitylation K5 0.619 0.462 _(ac)MQNYK(gl)YDK_
PPAP2B Ubiquitylation K15 -0.741 -0.668 _AIVPESK(gl)NGGSPALNNNPR_

Background Information for PPAP2B:


Pubmed-PPAP2B »
Uniprot-PPAP2B »
Biogrid-PPAP2B »
ProteomicsDB-PPAP2B »

Tumorportal-PPAP2B »
COSMIC-PPAP2B »
GenomeRNAi-PPAP2B »
Genecards-PPAP2B


Protein-protein Interactions for PPAP2B
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in PPAP2B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P_Acid_Pase_2/haloperoxidase IPR000326 0


Protein complexes (CORUM database) featuring PPAP2B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2366 ITGAV-ITGB3-PPAP2b complex Database 0


Categories featuring PPAP2B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0016020 membrane Database 0.52
Category members Pathway Pathway_71 KEGG_GLYCEROLIPID_METABOLISM 0 0.45
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0005912 adherens junction Database 0.25
Category members GO Category GO:0008354 germ cell migration Database 0.21
Category members GO Category GO:0004721 phosphoprotein phosphatase activity Database 0.11
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members Pathway Pathway_499 KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS 0 0.1
Category members GO Category GO:0005178 integrin binding Database 0.09
Category members GO Category GO:0030111 regulation of Wnt signaling pathway Database 0.08
Category members GO Category GO:0050821 protein stabilization Database 0.04
Category members GO Category GO:0001933 negative regulation of protein phosphorylation Database 0.04
Category members Pathway Pathway_100 REACTOME_PHOSPHOLIPID_METABOLISM 0 0
Category members Pathway Pathway_127 KEGG_SPHINGOLIPID_METABOLISM 0 0
Category members Pathway Pathway_128 REACTOME_SPHINGOLIPID_METABOLISM 0 0
Category members Pathway Pathway_276 KEGG_GLYCEROPHOSPHOLIPID_METABOLISM 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members Pathway Pathway_497 KEGG_ETHER_LIPID_METABOLISM 0 0
Category members Pathway Pathway_498 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS 0 0
Category members GO Category GO:0001568 blood vessel development Database 0
Category members GO Category GO:0001702 gastrulation with mouth forming second Database 0
Category members GO Category GO:0006629 lipid metabolic process Database 0
Category members GO Category GO:0006644 phospholipid metabolic process Database 0
Category members GO Category GO:0006665 sphingolipid metabolic process Database 0
Category members GO Category GO:0007155 cell adhesion Database 0
Category members GO Category GO:0008195 phosphatidate phosphatase activity Database 0
Category members GO Category GO:0016337 cell-cell adhesion Database 0
Category members GO Category GO:0030148 sphingolipid biosynthetic process Database 0
Category members GO Category GO:0034109 homotypic cell-cell adhesion Database 0
Category members GO Category GO:0042577 lipid phosphatase activity Database 0
Category members GO Category GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation Database 0
Category members GO Category GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity Database 0
Category members GO Category GO:0060070 canonical Wnt signaling pathway Database 0


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