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Query: MED30

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MED30 1 -0.285 2.100 -1.330

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MED30 Phosphorylation S2 -0.188 -0.097 _(ac)S(ph)TPPLAASGMAPGPFAGPQAQQAAR_
MED30 Phosphorylation T3 -0.188 -0.624 _(ac)ST(ph)PPLAASGMAPGPFAGPQAQQAAR_

Background Information for MED30:


Pubmed-MED30 »
Uniprot-MED30 »
Biogrid-MED30 »
ProteomicsDB-MED30 »

Tumorportal-MED30 »
COSMIC-MED30 »
GenomeRNAi-MED30 »
Genecards-MED30


Protein-protein Interactions for MED30
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BIRC5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MED1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MED18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MED19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MED21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MED7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POLR2G Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MED30
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring MED30
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 230 Mediator complex Database 0.76
Category members Corum 5450 Mediator complex Database 0.45


Categories featuring MED30
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0030521 androgen receptor signaling pathway Database 1.25
Category members Pathway Pathway_90 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION 0 0.88
Category members GO Category GO:0016592 mediator complex Database 0.53
Category members GO Category GO:0019827 stem cell maintenance Database 0.48
Category members Pathway Pathway_41 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION 0 0.35
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0006367 transcription initiation from RNA polymerase II promoter Database 0.25
Category members Pathway Pathway_1 REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM 0 0.23
Category members GO Category GO:0003712 transcription cofactor activity Database 0.21
Category members GO Category GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity Database 0.12
Category members Pathway Pathway_822 REACTOME_GENERIC_TRANSCRIPTION_PATHWAY 0 0.09
Category members GO Category GO:0001104 RNA polymerase II transcription cofactor activity Database 0.08
Category members GO Category GO:0046966 thyroid hormone receptor binding Database 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members GO Category GO:0004872 receptor activity Database 0
Category members GO Category GO:0030518 intracellular steroid hormone receptor signaling pathway Database 0
Category members GO Category GO:0042809 vitamin D receptor binding Database 0


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