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Query: HOXA11

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HOXA11 0 0.594 -0.050 0.240

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HOXA11 Phosphorylation S84 0.313 0.946 _GNLAHCYS(ph)AEELVHR_
HOXA11 Ubiquitylation K72 -0.905 _EYAIEPATK(gl)WHPR_

Background Information for HOXA11:


Pubmed-HOXA11 »
Uniprot-HOXA11 »
Biogrid-HOXA11 »
ProteomicsDB-HOXA11 »

Tumorportal-HOXA11 »
COSMIC-HOXA11 »
GenomeRNAi-HOXA11 »
Genecards-HOXA11


Protein-protein Interactions for HOXA11
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in HOXA11
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Homeobox_dom IPR001356 0.63
Category members Homeobox_metazoa IPR020479 0.28
Category members Homeodomain-like IPR009057 0
Category members DUF3528 IPR021918 0


Protein complexes (CORUM database) featuring HOXA11
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HOXA11
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0048589 developmental growth Database 0.45
Category members GO Category GO:0007275 multicellular organismal development Database 0.31
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0005667 transcription factor complex Database 0.19
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members GO Category GO:0009952 anterior/posterior pattern specification Database 0.06
Category members GO Category GO:0009954 proximal/distal pattern formation Database 0.04
Category members GO Category GO:0001656 metanephros development Database 0
Category members GO Category GO:0001501 skeletal system development Database 0
Category members GO Category GO:0001658 branching involved in ureteric bud morphogenesis Database 0
Category members GO Category GO:0001759 organ induction Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007501 mesodermal cell fate specification Database 0
Category members GO Category GO:0009653 anatomical structure morphogenesis Database 0
Category members GO Category GO:0009953 dorsal/ventral pattern formation Database 0
Category members GO Category GO:0010720 positive regulation of cell development Database 0
Category members GO Category GO:0030326 embryonic limb morphogenesis Database 0
Category members GO Category GO:0032330 regulation of chondrocyte differentiation Database 0
Category members GO Category GO:0032332 positive regulation of chondrocyte differentiation Database 0
Category members GO Category GO:0032993 protein-DNA complex Database 0
Category members GO Category GO:0035115 embryonic forelimb morphogenesis Database 0
Category members GO Category GO:0042733 embryonic digit morphogenesis Database 0
Category members GO Category GO:0060272 embryonic skeletal joint morphogenesis Database 0
Category members GO Category GO:0060351 cartilage development involved in endochondral bone morphogenesis Database 0


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