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Query: HEXB

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HEXB 0 0.163 -0.370 0.060 0.103

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for HEXB:


Pubmed-HEXB »
Uniprot-HEXB »
Biogrid-HEXB »
ProteomicsDB-HEXB »

Tumorportal-HEXB »
COSMIC-HEXB »
GenomeRNAi-HEXB »
Genecards-HEXB


Protein-protein Interactions for HEXB
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BACH1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF19 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP214 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMC6 Cat. description Hein, Mann, Cell 2015
Category members IP bait SOD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TGS1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TSNAX Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBA3C;TUBA3E Cat. description Hein, Mann, Cell 2015
Category members IP bait HEXA Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HEXB
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Glyco_hydro_20_cat-core IPR015883 0.04
Category members HEX_bac_N IPR015882 0
Category members Glycoside_hydrolase_SF IPR017853 0
Category members Beta_hexosaminidase_sua/sub IPR025705 0
Category members Chitobiase/Hex_dom_2-like IPR029018 0


Protein complexes (CORUM database) featuring HEXB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HEXB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members Pathway Pathway_73 REACTOME_GLYCOSAMINOGLYCAN_METABOLISM 0 1.71
Category members GO Category GO:0030203 glycosaminoglycan metabolic process Database 1.44
Category members Pathway Pathway_471 REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM 0 0.6
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0030204 chondroitin sulfate metabolic process Database 0.36
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_34 REACTOME_METABOLISM_OF_CARBOHYDRATES 0 0.31
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0042339 keratan sulfate metabolic process Database 0.24
Category members Pathway Pathway_112 REACTOME_KERATAN_SULFATE_KERATIN_METABOLISM 0 0.2
Category members Pathway Pathway_75 KEGG_GLYCOSAMINOGLYCAN_DEGRADATION 0 0.17
Category members GO Category GO:0042552 myelination Database 0.16
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members Pathway Pathway_470 REACTOME_CS_DS_DEGRADATION 0 0.11
Category members GO Category GO:0030207 chondroitin sulfate catabolic process Database 0.11
Category members GO Category GO:0048477 oogenesis Database 0.11
Category members Pathway Pathway_78 REACTOME_HYALURONAN_METABOLISM 0 0.1
Category members GO Category GO:0008219 cell death Database 0.08
Category members GO Category GO:0030212 hyaluronan metabolic process Database 0.08
Category members GO Category GO:0005975 carbohydrate metabolic process Database 0.07
Category members GO Category GO:0043202 lysosomal lumen Database 0.07
Category members Pathway Pathway_61 KEGG_AMINO_SUGAR_AND_NUCLEOTIDE_SUGAR_METABOLISM 0 0.04
Category members Pathway Pathway_80 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION 0 0.04
Category members GO Category GO:0050885 neuromuscular process controlling balance Database 0.02
Category members Pathway Pathway_100 REACTOME_PHOSPHOLIPID_METABOLISM 0 0
Category members Pathway Pathway_125 KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_GLOBO_SERIES 0 0
Category members Pathway Pathway_126 REACTOME_GLYCOSPHINGOLIPID_METABOLISM 0 0
Category members Pathway Pathway_128 REACTOME_SPHINGOLIPID_METABOLISM 0 0
Category members Pathway Pathway_129 KEGG_OTHER_GLYCAN_DEGRADATION 0 0
Category members Pathway Pathway_130 KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_GANGLIO_SERIES 0 0
Category members Pathway Pathway_131 REACTOME_KERATAN_SULFATE_DEGRADATION 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members Pathway Pathway_74 KEGG_LYSOSOME 0 0
Category members GO Category GO:0001501 skeletal system development Database 0
Category members GO Category GO:0001669 acrosomal vesicle Database 0
Category members GO Category GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds Database 0
Category members GO Category GO:0004563 beta-N-acetylhexosaminidase activity Database 0
Category members GO Category GO:0005764 lysosome Database 0
Category members GO Category GO:0006665 sphingolipid metabolic process Database 0
Category members GO Category GO:0006687 glycosphingolipid metabolic process Database 0
Category members GO Category GO:0006689 ganglioside catabolic process Database 0
Category members GO Category GO:0006874 cellular calcium ion homeostasis Database 0
Category members GO Category GO:0007040 lysosome organization Database 0
Category members GO Category GO:0007338 single fertilization Database 0
Category members GO Category GO:0007341 penetration of zona pellucida Database 0
Category members GO Category GO:0007605 sensory perception of sound Database 0
Category members GO Category GO:0007626 locomotory behavior Database 0
Category members GO Category GO:0008360 regulation of cell shape Database 0
Category members GO Category GO:0008654 phospholipid biosynthetic process Database 0
Category members GO Category GO:0009313 oligosaccharide catabolic process Database 0
Category members GO Category GO:0019915 lipid storage Database 0
Category members GO Category GO:0019953 sexual reproduction Database 0
Category members GO Category GO:0030214 hyaluronan catabolic process Database 0
Category members GO Category GO:0042340 keratan sulfate catabolic process Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0043615 astrocyte cell migration Database 0
Category members GO Category GO:0050905 neuromuscular process Database 0


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