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Query: FKBP8

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FKBP8 0 -0.822 -1.260 1.670 -0.042 0.441
FKBP8 0 -0.822 -1.260 1.670 -1.108 -0.333 -1.072

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FKBP8 Ubiquitylation K258 -0.292 _GK(gl)VLAQQGEYSEAIPILR_
FKBP8 Ubiquitylation K217 -0.362 -0.356 _VK(gl)CLNNLAASQLK_
FKBP8 Ubiquitylation K278 -1.013 -0.590 _AALK(gl)LEPSNK_
FKBP8 Ubiquitylation K284 -0.086 _LEPSNK(gl)TIHAELSK_

Background Information for FKBP8:


Pubmed-FKBP8 »
Uniprot-FKBP8 »
Biogrid-FKBP8 »
ProteomicsDB-FKBP8 »

Tumorportal-FKBP8 »
COSMIC-FKBP8 »
GenomeRNAi-FKBP8 »
Genecards-FKBP8


Protein-protein Interactions for FKBP8
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATP6AP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait BMPR1A Cat. description Hein, Mann, Cell 2015
Category members IP bait JUNB Cat. description Hein, Mann, Cell 2015
Category members IP bait MAD2L1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MLH1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB5C Cat. description Hein, Mann, Cell 2015
Category members IP bait VAPA Cat. description Hein, Mann, Cell 2015
Category members IP bait XRCC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait ANKMY2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in FKBP8
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members TPR_1 IPR001440 1.39
Category members TPR-contain_dom IPR013026 0.97
Category members TPR_repeat IPR019734 0.93
Category members TPR_2 IPR013105 0.45
Category members PPIase_FKBP_dom IPR001179 0.31


Protein complexes (CORUM database) featuring FKBP8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 4158 HSP90-FKBP38-CAM-Ca(2+) complex Database 0
Category members Corum 5526 CALM1-FKBP38-BCL2 complex Database 0


Categories featuring FKBP8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0006457 protein folding Database 4.93
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0007224 smoothened signaling pathway Database 2.11
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_1023 PID_NFAT_3PATHWAY 0 1.46
Category members GO Category GO:0003755 peptidyl-prolyl cis-trans isomerase activity Database 1.31
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0000413 protein peptidyl-prolyl isomerization Database 0.25
Category members GO Category GO:0018208 peptidyl-proline modification Database 0.14
Category members GO Category GO:0030510 regulation of BMP signaling pathway Database 0.09
Category members GO Category GO:0005528 FK506 binding Database 0.06
Category members GO Category GO:0030513 positive regulation of BMP signaling pathway Database 0.05
Category members GO Category GO:0043010 camera-type eye development Database 0.05
Category members GO Category GO:0035264 multicellular organism growth Database 0.04
Category members GO Category GO:0021915 neural tube development Database 0.03
Category members GO Category GO:0001708 cell fate specification Database 0
Category members GO Category GO:0005740 mitochondrial envelope Database 0
Category members GO Category GO:0009953 dorsal/ventral pattern formation Database 0
Category members GO Category GO:0010468 regulation of gene expression Database 0
Category members GO Category GO:0021904 dorsal/ventral neural tube patterning Database 0
Category members GO Category GO:0030176 integral to endoplasmic reticulum membrane Database 0
Category members GO Category GO:0031966 mitochondrial membrane Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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