bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: EYA4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EYA4 2 4.910 -0.120 0.100

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
EYA4 Phosphorylation S4 2.607 2.311 _(ac)M(ox)EDS(ph)QDLNEQSVK_
EYA4 Ubiquitylation K513 -0.108 _NNVGGLLGPAK(gl)R_
EYA4 Phosphorylation S367 -1.041 -1.090 _NNPS(ph)PPPDSDLER_
EYA4 Ubiquitylation K587 -1.219 _IGK(gl)ESCFER_

Background Information for EYA4:


Pubmed-EYA4 »
Uniprot-EYA4 »
Biogrid-EYA4 »
ProteomicsDB-EYA4 »

Tumorportal-EYA4 »
COSMIC-EYA4 »
GenomeRNAi-EYA4 »
Genecards-EYA4


Protein-protein Interactions for EYA4
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PFDN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SIX1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SIX2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in EYA4
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members EYA_dom IPR006545 0
Category members HAD-like_dom IPR023214 0


Protein complexes (CORUM database) featuring EYA4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring EYA4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0007275 multicellular organismal development Database 0.31
Category members GO Category GO:0016568 chromatin modification Database 0.18
Category members Disease phenotype Autosomal_dominant_nonsyndromic_sensorineural_deafness_type_DFNA Autosomal dominant nonsyndromic sensorineural deafness type DFNA Database 0
Category members GO Category GO:0004725 protein tyrosine phosphatase activity Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007601 visual perception Database 0
Category members GO Category GO:0007605 sensory perception of sound Database 0
Category members GO Category GO:0009653 anatomical structure morphogenesis Database 0
Category members GO Category GO:0042474 middle ear morphogenesis Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0048839 inner ear development Database 0


.

© Copyright Svejstrup Laboratory 2015