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Query: CLIC4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CLIC4 0 1.383 -0.105

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CLIC4 Ubiquitylation K146 -0.028 0.596 _GLLK(gl)TLQK_
CLIC4 Ubiquitylation K106 -0.220 0.166 _YLK(gl)LSPK_
CLIC4 Ubiquitylation K199 0.892 0.090 _LHIVK(gl)VVAK_
CLIC4 Ubiquitylation K249 -0.463 _DEFTNTCPSDKEVEIAYSDVAK(gl)R_

Background Information for CLIC4:


Pubmed-CLIC4 »
Uniprot-CLIC4 »
Biogrid-CLIC4 »
ProteomicsDB-CLIC4 »

Tumorportal-CLIC4 »
COSMIC-CLIC4 »
GenomeRNAi-CLIC4 »
Genecards-CLIC4


Protein-protein Interactions for CLIC4
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ANAPC16 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDC16 Cat. description Hein, Mann, Cell 2015
Category members IP bait CLIC4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CLIC4
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Glutathione-S-Trfase_C-like IPR010987 0.23
Category members Thioredoxin-like_fold IPR012336 0.16
Category members Int_Cl_channel IPR002946 0.04


Protein complexes (CORUM database) featuring CLIC4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CLIC4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0015629 actin cytoskeleton Database 2.22
Category members GO Category GO:0016363 nuclear matrix Database 1.89
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0005911 cell-cell junction Database 1.4
Category members GO Category GO:0015630 microtubule cytoskeleton Database 1.34
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0030336 negative regulation of cell migration Database 0.85
Category members GO Category GO:0005813 centrosome Database 0.75
Category members GO Category GO:0030659 cytoplasmic vesicle membrane Database 0.62
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0030496 midbody Database 0.39
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0009986 cell surface Database 0.17
Category members GO Category GO:0005902 microvillus Database 0.13
Category members GO Category GO:0061299 retina vasculature morphogenesis in camera-type eye Database 0.08
Category members GO Category GO:0030154 cell differentiation Database 0.06
Category members GO Category GO:0051493 regulation of cytoskeleton organization Database 0.04
Category members GO Category GO:0035264 multicellular organism growth Database 0.04
Category members GO Category GO:0034707 chloride channel complex Database 0
Category members GO Category GO:0001525 angiogenesis Database 0
Category members GO Category GO:0001886 endothelial cell morphogenesis Database 0
Category members GO Category GO:0005247 voltage-gated chloride channel activity Database 0
Category members GO Category GO:0005254 chloride channel activity Database 0
Category members GO Category GO:0006821 chloride transport Database 0
Category members GO Category GO:0007035 vacuolar acidification Database 0
Category members GO Category GO:0009566 fertilization Database 0
Category members GO Category GO:0030216 keratinocyte differentiation Database 0
Category members GO Category GO:0035088 establishment or maintenance of apical/basal cell polarity Database 0
Category members GO Category GO:0045177 apical part of cell Database 0
Category members GO Category GO:0048754 branching morphogenesis of an epithelial tube Database 0
Category members GO Category GO:0071277 cellular response to calcium ion Database 0


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