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Query: CAPN2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CAPN2 0 2.341 -1.140 1.400 0.314
CAPN2 0 2.341 -1.140 1.400 0.522 0.716 -0.611

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for CAPN2:


Pubmed-CAPN2 »
Uniprot-CAPN2 »
Biogrid-CAPN2 »
ProteomicsDB-CAPN2 »

Tumorportal-CAPN2 »
COSMIC-CAPN2 »
GenomeRNAi-CAPN2 »
Genecards-CAPN2


Protein-protein Interactions for CAPN2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CHORDC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait JAK3 Cat. description Hein, Mann, Cell 2015
Category members IP bait B3GNT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CAPN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GNS Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LSP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PSG8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CAPN2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Peptidase_C2_calpain_cat IPR001300 0
Category members EF_hand_dom IPR002048 0
Category members Calpain_domain_III IPR022682 0
Category members Calpain_III IPR022683 0
Category members Calpain_cysteine_protease IPR022684 0


Protein complexes (CORUM database) featuring CAPN2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CAPN2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000785 chromatin Database 2.59
Category members Pathway Pathway_579 PID_ERBB1_DOWNSTREAM_PATHWAY 0 1.97
Category members Pathway Pathway_541 PID_FAK_PATHWAY 0 1.88
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_595 KEGG_FOCAL_ADHESION 0 1.08
Category members GO Category GO:0008092 cytoskeletal protein binding Database 0.5
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0030425 dendrite Database 0.26
Category members GO Category GO:0007520 myoblast fusion Database 0.11
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members GO Category GO:0008233 peptidase activity Database 0.02
Category members Pathway Pathway_1069 BIOCARTA_MCALPAIN_PATHWAY 0 0
Category members Pathway Pathway_1144 BIOCARTA_MEF2D_PATHWAY 0 0
Category members Pathway Pathway_29 KEGG_ALZHEIMERS_DISEASE 0 0
Category members Pathway Pathway_572 KEGG_APOPTOSIS 0 0
Category members GO Category GO:0001666 response to hypoxia Database 0
Category members GO Category GO:0001824 blastocyst development Database 0
Category members GO Category GO:0004198 calcium-dependent cysteine-type endopeptidase activity Database 0
Category members GO Category GO:0006508 proteolysis Database 0
Category members GO Category GO:0008234 cysteine-type peptidase activity Database 0
Category members GO Category GO:0016540 protein autoprocessing Database 0
Category members GO Category GO:0071230 cellular response to amino acid stimulus Database 0


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