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Query: AP3B1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
AP3B1 1 6.213 0.283 0.568 0.447

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
AP3B1 Ubiquitylation K74 3.486 _IVGM(ox)IAKGK(gl)_
AP3B1 Phosphorylation S276 0.667 0.762 _NFYES(ph)DDDQKEK_

Background Information for AP3B1:


Pubmed-AP3B1 »
Uniprot-AP3B1 »
Biogrid-AP3B1 »
ProteomicsDB-AP3B1 »

Tumorportal-AP3B1 »
COSMIC-AP3B1 »
GenomeRNAi-AP3B1 »
Genecards-AP3B1


Protein-protein Interactions for AP3B1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait DLG3 Cat. description Hein, Mann, Cell 2015
Category members IP bait LYPLAL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NLRP3 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP155 Cat. description Hein, Mann, Cell 2015
Category members IP bait SKA3 Cat. description Hein, Mann, Cell 2015
Category members IP bait YWHAZ Cat. description Hein, Mann, Cell 2015
Category members IP bait AP3M1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AP3M2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AP3S1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CAMKV Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CREB3L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DTNBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EDA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EIF2C3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPB41L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPB41L5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ERMAP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM9A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGF8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PES1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PIP4K2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM63A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TPCN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VASN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VTI1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in AP3B1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members Clathrin/coatomer_adapt-like_N IPR002553 0


Protein complexes (CORUM database) featuring AP3B1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 59 AP3 adapter complex Database 0.58
Category members Corum 652 AP3-BLOC1 complex Database 0


Categories featuring AP3B1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members Pathway Pathway_474 REACTOME_MEMBRANE_TRAFFICKING 0 1.14
Category members GO Category GO:0016192 vesicle-mediated transport Database 1.1
Category members Pathway Pathway_475 REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING 0 0.98
Category members GO Category GO:0005765 lysosomal membrane Database 0.82
Category members Pathway Pathway_520 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS 0 0.78
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0019903 protein phosphatase binding Database 0.33
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0030665 clathrin-coated vesicle membrane Database 0.24
Category members GO Category GO:0030123 AP-3 adaptor complex Database 0.05
Category members GO Category GO:0019882 antigen processing and presentation Database 0.03
Category members GO Category GO:0006622 protein targeting to lysosome Database 0.02
Category members Pathway Pathway_74 KEGG_LYSOSOME 0 0
Category members Disease phenotype HERMANSKY-PUDLAK_SYNDROME_1 HERMANSKY-PUDLAK SYNDROME 1 Database 0
Category members GO Category GO:0008089 anterograde axon cargo transport Database 0
Category members GO Category GO:0030117 membrane coat Database 0
Category members GO Category GO:0032438 melanosome organization Database 0
Category members GO Category GO:0048007 antigen processing and presentation, exogenous lipid antigen via MHC class Ib Database 0
Category members GO Category GO:0048490 anterograde synaptic vesicle transport Database 0
Category members GO Category GO:0051138 positive regulation of NK T cell differentiation Database 0


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