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Results for the Category
REACTOME_UNWINDING_OF_DNA
(Pathway_868)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
MCM2 2 0.740 -0.140 0.552 0.052
MCM2 2 0.740 -0.140 1.288
MCM2 2 0.740 -0.140
MCM6 2 -0.170 -0.180 1.067 0.473 -0.065
MCM3 1 -1.860 3.650 1.197 0.554 0.207
CDC45 0 -0.450 0.240 0.247 -0.108 0.308 -1.985
MCM5 0 -0.890 1.090
MCM5 0 -0.890 1.090 0.660 0.490 0.195
GINS1 0 0.330 -0.860
MCM4 0 0.700 0.170 0.876 0.344 -0.023 0.237 0.753
MCM8 0 -0.350 0.360 0.876 0.344 -0.023 0.237 0.753
MCM8 0 -0.350 0.360
MCM7 0 -0.260 -0.010 0.361 -0.040
MCM7 0 -0.260 -0.010 0.592

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
CDC45 Ubiquitylation K514 0.237 -1.244 _SFVCSTK(gl)NRR_
CDC45 Ubiquitylation K560 -0.065 -0.647 _AFEK(gl)AAESTSSR_
GINS1 Ubiquitylation K5 -0.498 _MFCEK(gl)AMELIR_
GINS1 Ubiquitylation K51 -1.124 -0.716 _ALYEQNQSDVNEAK(gl)SGGR_
GINS1 Ubiquitylation K63 0.170 -0.428 _SDLIPTIK(gl)FR_
MCM2 Phosphorylation S4 0.060 -0.102 _(ac)AES(ph)SESFTM(ox)ASS(ph)PAQR_
MCM2 Phosphorylation S5 0.653 0.313 _(ac)AESS(ph)ESFTMASSPAQR_
MCM2 Phosphorylation T9 0.528 0.894 _(ac)AESSESFT(ph)MASSPAQR_
MCM2 Phosphorylation S12 0.027 0.508 _AESSESFTMAS(ph)SPAQR_
MCM2 Phosphorylation S13 0.595 0.841 _(ac)AESSESFTMASS(ph)PAQR_
MCM2 Phosphorylation S26 0.334 0.204 _GNDPLTS(ph)SPGR_
MCM2 Phosphorylation S27 0.076 0.378 _GNDPLTSS(ph)PGR_
MCM2 Phosphorylation S40 0.648 1.028 _TDALTS(ph)SPGR_
MCM2 Phosphorylation S41 0.613 0.869 _RTDALTSS(ph)PGR_
MCM2 Phosphorylation T106 2.035 2.162 _AIPELDAYEAEGLALDDEDVEELT(ph)ASQR_
MCM2 Phosphorylation S108 1.832 2.212 _AIPELDAYEAEGLALDDEDVEELTAS(ph)QR_
MCM2 Phosphorylation S139 0.404 0.482 _GLLYDS(ph)DEEDEERPAR_
MCM2 Ubiquitylation K205 0.225 0.747 _ISDMCK(gl)ENR_
MCM2 Ubiquitylation K365 -0.341 0.407 _IQESPGK(gl)VAAGR_
MCM2 Ubiquitylation K450 0.216 0.470 _MITSLSK(gl)DQQIGEK_
MCM2 Ubiquitylation K946 -0.032 _FSHDLK(gl)R_
MCM3 Ubiquitylation K198 -0.209 -1.171 _SVHYCPATKK(gl)_
MCM3 Phosphorylation S205 0.571 -0.326 _RYS(ph)DLTTLVAFPSSSVYPTK_
MCM3 Phosphorylation T209 0.700 0.517 _RYSDLTT(ph)LVAFPSSSVYPTK_
MCM3 Ubiquitylation K293 0.760 -0.751 _K(gl)GGYTSGTFR_
MCM3 Ubiquitylation K311 0.886 1.210 _TVLIACNVK(gl)QMSK_
MCM3 Ubiquitylation K480 0.706 0.010 _VTIAK(gl)AGIHAR_
MCM3 Ubiquitylation K508 -0.031 _YDQYK(gl)TPMENIGLQDSLLSR_
MCM3 Phosphorylation S713 0.697 _S(ph)EDESETEDEEEKSQEDQEQK_
MCM3 Phosphorylation S717 0.009 0.302 _SEDES(ph)ETEDEEEK_
MCM3 Phosphorylation S756 -0.581 -0.455 _DGDSYDPYDFS(ph)DTEEEMPQVHTPK_
MCM3 Phosphorylation T758 -0.622 _DGDSYDPYDFS(ph)DTEEEM(ox)PQVHTPK_
MCM3 Phosphorylation T767 -0.699 -0.088 _DGDSYDPYDFSDTEEEMPQVHT(ph)PK_
MCM3 Ubiquitylation K777 -0.521 _TADSQETK(gl)ESQKVELSESR_
MCM3 Ubiquitylation K781 -0.081 -0.408 _ESQK(gl)VELSESR_
MCM4 Phosphorylation S26 -0.380 0.511 _ATPAQTPRS(ph)EDAR_
MCM4 Phosphorylation S131 0.424 0.474 _GLQVDLQS(ph)DGAAAEDIVASEQSLGQK_
MCM4 Ubiquitylation K220 -0.271 0.326 _SFDK(gl)NLYR_
MCM4 Phosphorylation S326 0.118 0.226 _IAEPS(ph)VCGR_
MCM4 Ubiquitylation K353 -0.534 _SLFSDKQMIK(gl)_
MCM4 Ubiquitylation K409 0.140 -0.445 _VSNVK(gl)SVYK_
MCM4 Ubiquitylation K450 -0.607 _VELLK(gl)ELSR_
MCM4 Ubiquitylation K478 -0.439 _LASALAPSIYEHEDIKK(gl)_
MCM4 Ubiquitylation K536 -0.941 -0.853 _GQYTSGK(gl)GSSAVGLTAYVMKDPETR_
MCM4 Ubiquitylation K549 -0.023 -0.647 _GSSAVGLTAYVMK(gl)DPETR_
MCM4 Ubiquitylation K628 -1.124 -3.224 _TSVLAAANPIESQWNPKK(gl)_
MCM4 Ubiquitylation K746 -0.079 _LAEAHAK(gl)VR_
MCM4 Ubiquitylation K752 -0.885 -0.700 _LSNK(gl)VEAIDVEEAK(gl)R_
MCM4 Ubiquitylation K762 -0.483 -0.551 _VEAIDVEEAK(gl)R_
MCM4 Ubiquitylation K770 -0.963 -0.688 _EALK(gl)QSATDPR_
MCM4 Ubiquitylation K814 -1.087 _GK(gl)TPALK_
MCM4 Ubiquitylation K858 0.042 _ALADDDFLTVTGK(gl)TVR_
MCM5 Phosphorylation S2 0.212 0.649 _S(ph)GFDDPGIFYSDSFGGDAQADEGQAR_
MCM5 Phosphorylation S14 1.191 _(ac)SGFDDPGIFYSDS(ph)FGGDAQADEGQAR_
MCM5 Ubiquitylation K392 -0.464 -0.556 _SQLLK(gl)FVEK_
MCM5 Ubiquitylation K583 0.060 -0.670 _LSAEAAEKLK(gl)_
MCM6 Phosphorylation S13 4.283 4.775 _(ac)M(ox)DLAAAAEPGAGS(ph)QHLEVRDEVAEK_
MCM6 Ubiquitylation K95 0.656 _ALK(gl)TFVK_
MCM6 Ubiquitylation K197 0.461 0.797 _FLLDTNK(gl)SR_
MCM6 Ubiquitylation K332 0.272 0.709 _NQMTVK(gl)EWEK_
MCM6 Ubiquitylation K422 0.854 _AVYTSGK(gl)ASSAAGLTAAVVR_
MCM6 Ubiquitylation K490 0.630 _AGVK(gl)ATLNAR_
MCM6 Ubiquitylation K517 0.150 -0.502 _SLK(gl)QNINLSAPIMSR_
MCM6 Ubiquitylation K611 1.032 0.016 _DGSGVTK(gl)SSWR_
MCM6 Ubiquitylation K643 -0.198 _MHCCDEVQPK(gl)HVK_
MCM6 Ubiquitylation K654 0.288 -0.028 _LLNK(gl)SIIR_
MCM6 Ubiquitylation K744 -0.152 -0.415 _KVEEEEDESALK(gl)R_
MCM6 Phosphorylation S758 0.528 2.700 _EIES(ph)EIDSEEELINK_
MCM6 Phosphorylation S762 1.561 1.325 _EIESEIDS(ph)EEELINK_
MCM6 Ubiquitylation K775 0.748 _IIEK(gl)VIHR_
MCM7 Ubiquitylation K4 -1.164 _(ac)ALK(gl)DYALEKEK_
MCM7 Ubiquitylation K10 -0.334 -1.453 _(ac)ALKDYALEK(gl)EK_
MCM7 Ubiquitylation K12 -1.492 _DYALEK(gl)EK_
MCM7 Ubiquitylation K28 -0.102 -0.861 _FLQEFYQDDELGK(gl)K_
MCM7 Ubiquitylation K29 -1.023 -0.094 _FLQEFYQDDELGKK(gl)QFK_
MCM7 Ubiquitylation K32 0.146 -0.970 _QFK(gl)YGNQLVR_
MCM7 Ubiquitylation K89 -1.906 -1.328 _LFADAVQELLPQYK(gl)ER_
MCM7 Phosphorylation S121 0.902 0.509 _S(ph)PQNQYPAELMR_
MCM7 Ubiquitylation K145 -2.703 _RFELYFQGPSSNK(gl)PR_
MCM7 Ubiquitylation K159 0.038 -0.495 _ADSVGK(gl)LVTVR_
MCM7 Ubiquitylation K231 -0.965 _FIK(gl)FQEMK_
MCM7 Ubiquitylation K236 -1.769 _FQEMK(gl)MQEHSDQVPVGNIPR_
MCM7 Ubiquitylation K352 -1.468 _LAASIAPEIYGHEDVKK(gl)_
MCM7 Ubiquitylation K557 -2.556 -2.098 _QPPSQFEPLDMK(gl)LMR_
MCM7 Ubiquitylation K596 -0.751 -0.539 _REAWASK(gl)DATYTSAR_
MCM7 Ubiquitylation K627 -0.965 -0.588 _MVDVVEK(gl)EDVNEAIR_
MCM7 Ubiquitylation K641 -0.836 -0.945 _LMEMSK(gl)DSLLGDKGQTAR_
MCM7 Ubiquitylation K648 -0.422 -0.441 _DSLLGDK(gl)GQTAR_
MCM8 Phosphorylation S26 -0.380 0.511 _ATPAQTPRS(ph)EDAR_
MCM8 Phosphorylation S131 0.424 0.474 _GLQVDLQS(ph)DGAAAEDIVASEQSLGQK_
MCM8 Ubiquitylation K208 1.456 _VYNYEPLTQLK(gl)NVR_
MCM8 Ubiquitylation K220 -0.271 0.326 _SFDK(gl)NLYR_
MCM8 Ubiquitylation K263 -0.018 _YSLPTK(gl)CPVPVCR_
MCM8 Phosphorylation S326 0.118 0.226 _IAEPS(ph)VCGR_
MCM8 Ubiquitylation K353 -0.534 _SLFSDKQMIK(gl)_
MCM8 Ubiquitylation K409 0.140 -0.445 _VSNVK(gl)SVYK_
MCM8 Ubiquitylation K450 -0.607 _VELLK(gl)ELSR_
MCM8 Ubiquitylation K478 -0.439 _LASALAPSIYEHEDIKK(gl)_
MCM8 Ubiquitylation K536 -0.941 -0.853 _GQYTSGK(gl)GSSAVGLTAYVMKDPETR_
MCM8 Ubiquitylation K549 -0.023 -0.647 _GSSAVGLTAYVMK(gl)DPETR_
MCM8 Ubiquitylation K611 -1.605 _TSIIAAANPVGGHYNKAK(gl)_
MCM8 Ubiquitylation K628 -1.124 -3.224 _TSVLAAANPIESQWNPKK(gl)_
MCM8 Ubiquitylation K746 -0.079 _LAEAHAK(gl)VR_
MCM8 Ubiquitylation K752 -0.885 -0.700 _LSNK(gl)VEAIDVEEAK(gl)R_
MCM8 Ubiquitylation K762 -0.483 -0.551 _VEAIDVEEAK(gl)R_
MCM8 Ubiquitylation K770 -0.963 -0.688 _EALK(gl)QSATDPR_
MCM8 Ubiquitylation K814 -1.087 _GK(gl)TPALK_
MCM8 Ubiquitylation K858 0.042 _ALADDDFLTVTGK(gl)TVR_


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