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Query: GINS1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GINS1 0 -0.258 0.330 -0.860

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
GINS1 Ubiquitylation K63 0.170 -0.428 _SDLIPTIK(gl)FR_
GINS1 Ubiquitylation K5 -0.498 _MFCEK(gl)AMELIR_
GINS1 Ubiquitylation K51 -1.124 -0.716 _ALYEQNQSDVNEAK(gl)SGGR_

Background Information for GINS1:





Protein-protein Interactions for GINS1

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCDC84 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CSNK1G2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GINS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GTF2E2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MCM7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TIPIN Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in GINS1

Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring GINS1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 678 GINS complex Database 0.1


Categories featuring GINS1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members Pathway Pathway_323 REACTOME_DNA_REPLICATION 0 5.24
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members GO Category GO:0006260 DNA replication Database 3.34
Category members Pathway Pathway_315 REACTOME_S_PHASE 0 2.19
Category members Pathway Pathway_330 REACTOME_SYNTHESIS_OF_DNA 0 1.96
Category members GO Category GO:0006271 DNA strand elongation involved in DNA replication Database 1.33
Category members Pathway Pathway_327 REACTOME_DNA_STRAND_ELONGATION 0 0.9
Category members Pathway Pathway_868 REACTOME_UNWINDING_OF_DNA 0 0.44
Category members GO Category GO:0001833 inner cell mass cell proliferation Database 0


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