Results for the Category
REACTOME_SIGNALING_BY_NOTCH4
(Pathway_1280)
RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
W | |||||||
Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
---|---|---|---|---|---|---|---|---|
APH1B | 1 | -1.760 | 3.070 | |||||
PSEN2 | 1 | -1.820 | 3.280 | |||||
PSEN1 | 0 | 0.930 | -1.110 | |||||
JAG1 | 0 | -0.260 | 0.070 | |||||
ADAM10 | 0 | 1.400 | -1.040 | -0.111 | 0.009 | |||
NCSTN | 0 | -1.540 | 2.100 | 0.618 | 0.379 | |||
JAG2 | 0 | -0.170 | 0.020 | |||||
PSENEN | 0 | -0.550 | 0.740 |
Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
---|---|---|---|---|---|
ADAM10 | Ubiquitylation | K721 | -2.406 | _LPPPKPLPGTLK(gl)R_ | |
APH1B | Ubiquitylation | K102 | -0.148 | _ASEGLK(gl)SINPGETAPSMR_ | |
JAG1 | Ubiquitylation | K1142 | -0.783 | _HGANTVPIKDYENK(gl)_ | |
JAG2 | Ubiquitylation | K76 | 1.283 | _VCLK(gl)EYQAK_ | |
JAG2 | Phosphorylation | T1155 | -0.335 | -0.737 | _NFT(ph)PPPR_ |
JAG2 | Ubiquitylation | K1200 | 0.117 | _FLSHK(gl)FTK_ | |
NCSTN | Ubiquitylation | K110 | 1.107 | _DLMEK(gl)LK_ | |
PSEN1 | Phosphorylation | S313 | 0.844 | _VSKNS(ph)KYNAESTER_ | |
PSEN1 | Ubiquitylation | K314 | 0.016 | 0.414 | _NSK(gl)YNAESTER_ |
PSEN1 | Phosphorylation | S366 | -0.340 | 0.055 | _AAVQELSS(ph)SILAGEDPEER_ |
PSEN1 | Phosphorylation | S367 | 0.005 | 0.066 | _AAVQELSSS(ph)ILAGEDPEER_ |
PSEN2 | Phosphorylation | S58 | -0.112 | -0.130 | _TSLM(ox)SAES(ph)PTPR_ |
PSENEN | Ubiquitylation | K11 | 0.476 | _VSNEEK(gl)LNLCR_ |
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