Results for the Category
negative regulation by host of viral transcription
(GO:0043922)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| JUN | 3 | -0.930 | 0.930 | -0.126 | ||||
| TFAP4 | 1 | 1.270 | -0.790 | |||||
| HDAC1 | 1 | -1.980 | 4.450 | |||||
| HDAC1 | 1 | -1.980 | 4.450 | -0.122 | 0.307 | 0.969 | 0.094 | 0.191 |
| POU2F3 | 1 | -0.780 | 0.990 | |||||
| REST | 0 | -0.120 | -0.050 | -0.002 | -1.235 | -0.636 | ||
| TARDBP | 0 | -1.050 | 1.160 | -0.359 | -1.276 | -0.495 | -0.408 | 0.021 |
| ZNF639 | 0 | -0.250 | -0.510 | -0.298 | 0.605 | |||
| INPP5K | 0 | -0.690 | 1.160 | |||||
| HMGA2 | 0 | 0.340 | -0.490 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| HDAC1 | Ubiquitylation | K50 | 0.036 | _K(gl)MEIYRPHK_ | |
| HDAC1 | Ubiquitylation | K66 | -0.593 | _ANAEEMTK(gl)YHSDDYIK_ | |
| HDAC1 | Ubiquitylation | K74 | 0.620 | -1.473 | _YHSDDYIK(gl)FLR_ |
| HDAC1 | Ubiquitylation | K89 | 0.749 | -0.241 | _SIRPDNMSEYSK(gl)QMQR_ |
| HDAC1 | Phosphorylation | S393 | -1.133 | -1.144 | _M(ox)LPHAPGVQM(ox)QAIPEDAIPEES(ph)GDEDEDDPDKR_ |
| HDAC1 | Phosphorylation | S409 | 1.326 | 1.144 | _ISICS(ph)SDKR_ |
| HDAC1 | Phosphorylation | S410 | 1.326 | 1.144 | _ISICS(ph)SDKR_ |
| HDAC1 | Ubiquitylation | K412 | 0.642 | -0.744 | _ISICSSDK(gl)R_ |
| HMGA2 | Phosphorylation | S44 | -0.564 | -0.762 | _KQQQEPTGEPS(ph)PK_ |
| HMGA2 | Phosphorylation | S105 | -0.055 | -0.046 | _KPAQEETEETSSQES(ph)AEED_ |
| INPP5K | Ubiquitylation | K248 | -0.741 | 0.167 | _LLFPPTYK(gl)FDR_ |
| JUN | Phosphorylation | S58 | -0.167 | -1.247 | _AKNS(ph)DLLTSPDVGLLK_ |
| JUN | Phosphorylation | T62 | 2.545 | 1.674 | _NSDLLT(ph)SPDVGLLK_ |
| JUN | Phosphorylation | S63 | 2.030 | 1.458 | _NSDLLTS(ph)PDVGLLK_ |
| JUN | Ubiquitylation | K70 | 9.213 | _NSDLLTSPDVGLLK(gl)_ | |
| JUN | Phosphorylation | S73 | 1.499 | 0.845 | _LAS(ph)PELER_ |
| JUN | Phosphorylation | S243 | -0.642 | -1.399 | _LQALKEEPQTVPEMPGETPPLS(ph)PIDMESQER_ |
| JUN | Ubiquitylation | K309 | 1.034 | 0.155 | _EQVAQLK(gl)QK_ |
| POU2F3 | Phosphorylation | S408 | 0.932 | 1.562 | _RTS(ph)IETNIR_ |
| REST | Ubiquitylation | K280 | 0.406 | _VYTCGK(gl)CNYFSDR_ | |
| REST | Phosphorylation | S864 | -3.456 | _ESVSTEDLSPPS(ph)PPLPK_ | |
| TARDBP | Ubiquitylation | K95 | 0.123 | _KMDETDASSAVK(gl)VK_ | |
| TARDBP | Ubiquitylation | K145 | 0.090 | _TGHSK(gl)GFGFVR_ | |
| TARDBP | Ubiquitylation | K160 | 0.720 | _FTEYETQVK(gl)VMSQR_ | |
| TARDBP | Ubiquitylation | K176 | -0.001 | 0.145 | _WCDCK(gl)LPNSK_ |
| TARDBP | Ubiquitylation | K181 | -0.479 | -0.804 | _LPNSK(gl)QSQDEPLR_ |
| TARDBP | Ubiquitylation | K263 | 0.619 | _GISVHISNAEPK(gl)HNSNR_ | |
| TFAP4 | Ubiquitylation | K114 | 1.008 | 2.315 | _LLQQNTQLK(gl)R_ |
| TFAP4 | Phosphorylation | S123 | 0.832 | _RFIQELSGS(ph)SPKR_ | |
| TFAP4 | Phosphorylation | S124 | 0.584 | 0.494 | _RFIQELSGSS(ph)PK_ |
| ZNF639 | Phosphorylation | S88 | 1.106 | 0.234 | _NQNYLVPS(ph)PVLR_ |
| ZNF639 | Ubiquitylation | K369 | 0.828 | _ITFDK(gl)CK_ |
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