bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Category

Results for the Category
RNA polymerase II carboxy-terminal domain kinase activity
(GO:0008353)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
GTF2H1 3 -0.470 0.340 0.260 2.656 2.859 1.092 0.966
ERCC2 2 -0.590 1.060 -0.491 1.066
CDK9 2 -1.000 1.130 2.047 1.362 1.840 1.146 0.280
ERCC3 2 -1.110 1.490 2.619 2.418 0.499
MNAT1 0 -0.030 -0.100 0.666
CDK13 0 -0.100 0.210 -0.507 -0.248
CCNK 0 -0.940 0.500 -1.137 -1.242 0.561 -0.665 0.806
CCNK 0 -0.940 0.500
GTF2H3 0 -0.020 0.680 1.408 0.908
CCNH 0 1.480 -0.550
CDK12 0 1.020 -0.690 -0.510 0.013
CDK1 0 -0.370 0.080 -0.202 -0.884 -0.107 -0.097 -0.501

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
CCNH Ubiquitylation K189 0.418 _K(gl)TADDFLNR_
CCNK Ubiquitylation K118 0.624 _DIIK(gl)TAR_
CCNK Phosphorylation S340 0.324 0.494 _RAVVVS(ph)PKEENK_
CDK1 Ubiquitylation K6 0.011 -0.784 _(ac)M(ox)EDYTK(gl)IEK_
CDK1 Ubiquitylation K20 -0.327 -0.270 _IGEGTYGVVYK(gl)GR_
CDK1 Ubiquitylation K33 0.736 0.239 _TTGQVVAMK(gl)K_
CDK1 Ubiquitylation K34 -0.306 _TTGQVVAMKK(gl)_
CDK1 Ubiquitylation K58 0.312 -0.262 _EISLLK(gl)ELR_
CDK1 Ubiquitylation K136 -0.468 _DLK(gl)PQNLLIDDK(gl)GTIK_
CDK1 Ubiquitylation K145 0.161 -0.954 _DLKPQNLLIDDK(gl)GTIK_
CDK1 Ubiquitylation K149 -0.038 _GTIK(gl)LADFGLAR_
CDK1 Ubiquitylation K251 -0.047 -1.236 _WK(gl)PGSLASHVK_
CDK1 Ubiquitylation K280 0.179 -1.210 _MLIYDPAK(gl)R_
CDK12 Phosphorylation S236 0.095 _QDDS(ph)PSGASYGQDYDLS(ph)PSR_
CDK12 Phosphorylation S249 0.095 _QDDS(ph)PSGASYGQDYDLS(ph)PSR_
CDK12 Phosphorylation S385 0.649 _HSSIS(ph)PVRLPLNSSLGAELSR_
CDK12 Phosphorylation S420 0.004 -0.202 _ES(ph)KGSPVFLPR_
CDK12 Phosphorylation S423 -0.155 -0.297 _GS(ph)PVFLPR_
CDK12 Phosphorylation T514 0.364 0.570 _DSKPIALKEEIVT(ph)PK_
CDK12 Phosphorylation S681 -2.532 -2.051 _HLLTDLPLPPELPGGDLS(ph)PPDS(ph)PEPK_
CDK12 Phosphorylation S685 -2.729 _HLLTDLPLPPELPGGDLS(ph)PPDS(ph)PEPK_
CDK12 Phosphorylation T692 -0.765 -1.849 _AIT(ph)PPQQPYK_
CDK12 Phosphorylation S1082 -1.661 -0.980 _KETTSGTSTEPVKNS(ph)SPAPPQPAPGK_
CDK12 Phosphorylation S1083 -1.093 -1.330 _NSS(ph)PAPPQPAPGK_
CDK12 Phosphorylation T1244 -0.956 _RT(ph)PTMPQEEAAACPPHILPPEK_
CDK13 Phosphorylation S383 -0.073 0.010 _GGDVS(ph)PSPYSSSSWR_
CDK13 Phosphorylation S493 -0.539 _ASNTS(ph)TPTKGNTETSASASQTNHVK_
CDK13 Phosphorylation T494 -0.207 _ASNTST(ph)PTKGNTETSASASQTNHVK_
CDK13 Phosphorylation S525 0.544 0.150 _IEHAPS(ph)PSSGGTLK_
CDK13 Phosphorylation S664 -0.641 _CLLADLPLPPELPGGDDLSKS(ph)PEEK_
CDK13 Phosphorylation T1246 -0.527 -0.133 _ILELT(ph)PEPDRPR_
CDK9 Ubiquitylation K35 -0.042 _IGQGTFGEVFK(gl)AR_
CDK9 Ubiquitylation K151 -0.345 _DMK(gl)AANVLITR_
CDK9 Ubiquitylation K178 -0.409 -1.058 _AFSLAK(gl)NSQPNR_
CDK9 Ubiquitylation K269 -1.874 _LELVK(gl)GQK_
ERCC2 Ubiquitylation K268 5.973 1.957 _CQGNLETLQK(gl)TVLR_
ERCC2 Ubiquitylation K507 -2.034 _GNDQVAISSK(gl)FETR_
GTF2H1 Ubiquitylation K240 2.338 _LNTGSK(gl)DLFAECAK_
GTF2H3 Ubiquitylation K28 -0.741 _QALK(gl)ESQFTLSK_
GTF2H3 Ubiquitylation K74 -0.538 _FLYPGK(gl)NGR_
GTF2H3 Ubiquitylation K125 -0.584 -0.425 _SDIK(gl)GQHTETLLAGSLAK_
GTF2H3 Ubiquitylation K152 -0.594 _MNKEVK(gl)DNQEMK_
GTF2H3 Ubiquitylation K300 -1.837 _ISLPPVLKAK(gl)_
MNAT1 Phosphorylation S279 0.003 0.225 _AAS(ph)PQDLAGGYTSSLACHR_


.

© Copyright Svejstrup Laboratory 2015