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Query: CDK13

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CDK13 0 0.149 -0.100 0.210 -0.507 -0.248

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CDK13 Phosphorylation S525 0.544 0.150 _IEHAPS(ph)PSSGGTLK_
CDK13 Phosphorylation S383 -0.073 0.010 _GGDVS(ph)PSPYSSSSWR_
CDK13 Phosphorylation T1246 -0.527 -0.133 _ILELT(ph)PEPDRPR_
CDK13 Phosphorylation S493 -0.539 _ASNTS(ph)TPTKGNTETSASASQTNHVK_
CDK13 Phosphorylation T494 -0.207 _ASNTST(ph)PTKGNTETSASASQTNHVK_
CDK13 Phosphorylation S664 -0.641 _CLLADLPLPPELPGGDDLSKS(ph)PEEK_

Background Information for CDK13:


Pubmed-CDK13 »
Uniprot-CDK13 »
Biogrid-CDK13 »
ProteomicsDB-CDK13 »

Tumorportal-CDK13 »
COSMIC-CDK13 »
GenomeRNAi-CDK13 »
Genecards-CDK13


Protein-protein Interactions for CDK13
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK13 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK4 Cat. description Hein, Mann, Cell 2015
Category members IP bait IKBKG Cat. description Hein, Mann, Cell 2015
Category members IP bait LCK Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK13 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait JPH4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR46 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CDK13
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring CDK13
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CDK13
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0016607 nuclear speck Database 4.84
Category members GO Category GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity Database 0.42
Category members GO Category GO:0007275 multicellular organismal development Database 0.31
Category members GO Category GO:0000380 alternative mRNA splicing, via spliceosome Database 0.29
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0004693 cyclin-dependent protein serine/threonine kinase activity Database 0.08
Category members GO Category GO:0007088 regulation of mitosis Database 0.07
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members GO Category GO:0008284 positive regulation of cell proliferation Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex Database 0
Category members GO Category GO:0030097 hemopoiesis Database 0
Category members GO Category GO:0030332 cyclin binding Database 0


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