Results for the Category
ER overload response
(GO:0006983)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| GSK3B | 2 | 1.020 | -0.870 | -1.128 | 1.091 | |||
| HSPA5 | 1 | -0.670 | 0.310 | -0.181 | -0.208 | 0.339 | -0.702 | -0.192 |
| CCDC47 | 0 | 0.850 | -0.930 | 0.233 | 0.184 | 0.318 | ||
| WFS1 | 0 | -0.390 | 0.420 | -0.793 | -0.234 | |||
| VIMP | 0 | 0.490 | -0.510 | -2.036 | ||||
| TP53 | 0 | -1.070 | 1.050 | -2.808 | 0.076 | -0.094 | 0.436 | 0.497 |
| PPP1R15B | 0 | 0.820 | -0.760 | |||||
| EIF2AK3 | 0 | 0.010 | 0.340 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| CCDC47 | Ubiquitylation | K351 | -2.212 | -0.647 | _IMQEEGQPLK(gl)LPDTK_ |
| CCDC47 | Ubiquitylation | K356 | -0.934 | _IMQEEGQPLKLPDTK(gl)R_ | |
| CCDC47 | Ubiquitylation | K419 | 0.483 | _VEENFLK(gl)LTHVQR_ | |
| EIF2AK3 | Phosphorylation | S715 | 0.832 | _EHIEIIAPS(ph)PQR_ | |
| GSK3B | Phosphorylation | S9 | -0.483 | 0.010 | _TTS(ph)FAESCKPVQQPSAFGSMK_ |
| GSK3B | Ubiquitylation | K85 | -0.204 | _LCDSGELVAIK(gl)K_ | |
| GSK3B | Ubiquitylation | K86 | -0.204 | _LCDSGELVAIK(gl)K_ | |
| GSK3B | Phosphorylation | S215 | 0.296 | 0.477 | _GEPNVS(ph)YICSR_ |
| GSK3B | Phosphorylation | Y216 | 0.356 | 0.376 | _GEPNVSY(ph)ICSR_ |
| GSK3B | Phosphorylation | T390 | 2.800 | 2.527 | _IQAAAST(ph)PTNATAASDANTGDR_ |
| HSPA5 | Ubiquitylation | K81 | -0.455 | _LIGDAAK(gl)NQLTSNPENTVFDAK(gl)R_ | |
| HSPA5 | Ubiquitylation | K96 | -0.392 | -0.109 | _NQLTSNPENTVFDAK(gl)R_ |
| HSPA5 | Ubiquitylation | K118 | 0.783 | _FLPFK(gl)VVEK_ | |
| HSPA5 | Ubiquitylation | K340 | 0.743 | _STMK(gl)PVQK_ | |
| HSPA5 | Ubiquitylation | K352 | -0.469 | 0.822 | _VLEDSDLK(gl)K_ |
| HSPA5 | Ubiquitylation | K353 | -0.469 | _VLEDSDLK(gl)K_ | |
| HSPA5 | Ubiquitylation | K447 | 3.097 | _NTVVPTKK(gl)_ | |
| HSPA5 | Ubiquitylation | K523 | -0.120 | 0.631 | _NK(gl)ITITNDQNR_ |
| PPP1R15B | Ubiquitylation | K705 | -1.323 | _LQGTCFK(gl)GLNVLK_ | |
| TP53 | Ubiquitylation | K120 | -0.188 | _LGFLHSGTAK(gl)SVTCTYSPALNK_ | |
| TP53 | Ubiquitylation | K164 | 0.157 | -1.260 | _AMAIYK(gl)QSQHMTEVVR_ |
| TP53 | Phosphorylation | S314 | -0.695 | -1.000 | _ALPNNTSS(ph)SPQPK_ |
| TP53 | Phosphorylation | S315 | -0.762 | -0.959 | _RALPNNTSSS(ph)PQPK_ |
| TP53 | Ubiquitylation | K320 | -0.978 | _ALPNNTSSSPQPKK(gl)_ | |
| TP53 | Ubiquitylation | K357 | -0.231 | -0.823 | _ELNEALELKDAQAGK(gl)EPGGSR_ |
| VIMP | Ubiquitylation | K117 | -2.952 | -1.705 | _AAAAVEPDVVVK(gl)R_ |
| VIMP | Ubiquitylation | K190 | -1.565 | -1.157 | _KPQEEDSPGPSTSSVLK(gl)R_ |
| WFS1 | Phosphorylation | S32 | 1.184 | 1.098 | _LNATAS(ph)LEQER_ |
| WFS1 | Ubiquitylation | K143 | 0.703 | _EAVK(gl)LLR_ |
.
© Copyright Svejstrup Laboratory 2015