RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
RUNX1T1	0	0.840	-0.680
GNAS	0	0.840	-0.750
GNAS	0	0.840	-0.750
GNAS	0	0.840	-0.750	-0.166	-0.094	0.032	0.420	0.504
MTHFD1	0	-0.470	0.110		0.477
MTHFD1	0	-0.470	0.110	0.256			0.731	0.774
PIK3CA	0
SMAD4	0	0.420	-0.390		0.020	0.556		-0.485
AKT1	0	-0.050	0.700
AKT1	0	0.860	-0.040
BRAF	0
WRN	0	-0.320	-0.170					0.180
SMAD3	0	-1.560	1.800
SMAD3	0	0.270	-0.340
CTNNB1	0	0.490	-0.230
CTNNB1	0	0.490	-0.230	-0.415			0.628	0.215
NF1	0	1.000	-0.500				0.444	-0.190

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
AKT1	Phosphorylation	S124	0.252	0.311	_SGS(ph)PSDNSGAEEMEVSLAKPK_
AKT1	Phosphorylation	S126	-0.241		_SGSPS(ph)DNSGAEEM(ox)EVSLAK_
AKT1	Ubiquitylation	K301	0.988		_EGIK(gl)DGATMK_
BRAF	Phosphorylation	S151	-0.685	-0.629	_SNPKS(ph)PQKPIVR_
BRAF	Phosphorylation	S363	-0.023	-0.241	_S(ph)SSAPNVHINTIEPVNIDDLIR_
BRAF	Phosphorylation	S365	-0.286	0.012	_SSS(ph)APNVHINTIEPVNIDDLIR_
BRAF	Phosphorylation	S399	-0.890	-0.527	_GDGGSTTGLS(ph)ATPPASLPGSLTNVK_
BRAF	Phosphorylation	T401	-0.525		_GDGGSTTGLSAT(ph)PPASLPGSLTNVK_
BRAF	Phosphorylation	S446	0.246	0.349	_RDS(ph)SDDWEIPDGQITVGQR_
BRAF	Phosphorylation	S447	0.579	0.623	_RDSS(ph)DDWEIPDGQITVGQR_
BRAF	Phosphorylation	S729	0.208	0.219	_SAS(ph)EPSLNR_
CTNNB1	Ubiquitylation	K158		-1.265	_AIPELTK(gl)LLNDEDQVVVNK_
CTNNB1	Ubiquitylation	K180	-0.546	-0.636	_AAVM(ox)VHQLSK(gl)K_
CTNNB1	Ubiquitylation	K181	-0.717	-0.729	_AAVMVHQLSKK(gl)_
CTNNB1	Phosphorylation	S191	-0.024	0.129	_S(ph)PQMVSAIVR_
CTNNB1	Ubiquitylation	K435		-0.350	_NK(gl)MM(ox)VCQVGGIEALVR_
CTNNB1	Ubiquitylation	K496		-1.262	_LHYGLPVVVK(gl)_
CTNNB1	Phosphorylation	S552	1.233	1.224	_RTS(ph)MGGTQQQFVEGVR_
CTNNB1	Phosphorylation	T556	1.275	0.995	_RTSM(ox)GGT(ph)QQQFVEGVR_
CTNNB1	Ubiquitylation	K671	-0.941	-0.934	_MSEDKPQDYK(gl)K_
GNAS	Ubiquitylation	K8	0.430	0.328	_GCLGNSK(gl)TEDQRNEEK(gl)AQR_
GNAS	Ubiquitylation	K17	-0.011		_GCLGNSK(gl)TEDQRNEEK(gl)AQR_
GNAS	Ubiquitylation	K32	0.249	-0.446	_QLQK(gl)DKQVYR_
GNAS	Ubiquitylation	K58	-1.182	0.161	_STIVK(gl)QM(ox)R_
GNAS	Ubiquitylation	K92	-1.333	-0.290	_ATK(gl)VQDIKNNLK_
GNAS	Ubiquitylation	K97		0.076	_VQDIK(gl)NNLK_
GNAS	Ubiquitylation	K167	-1.721		_LHALK(gl)LR_
GNAS	Ubiquitylation	K301	-0.955	-0.198	_QDLLAEK(gl)VLAGK_
GNAS	Ubiquitylation	K308		-0.472	_SK(gl)IEDYFPEFAR_
MTHFD1	Ubiquitylation	K114	0.313		_LK(gl)AAEEIGIK_
MTHFD1	Ubiquitylation	K644	0.727	0.588	_LGK(gl)MVVASSK_
MTHFD1	Ubiquitylation	K740		0.576	_FFNIK(gl)CR_
MTHFD1	Ubiquitylation	K795		-0.151	_GFSNLK(gl)K_
MTHFD1	Ubiquitylation	K910	-0.200		_AEVYTK(gl)QGFGNLPICMAK_
NF1	Ubiquitylation	K471		0.218	_MAPSLTFKEK(gl)_
NF1	Phosphorylation	S864		-0.458	_SNSGLATYS(ph)PPMGPVSER_
NF1	Phosphorylation	T2514		0.076	_GSEGYLAATYPTVGQT(ph)SPR_
NF1	Phosphorylation	S2515	0.071	0.316	_GSEGYLAATYPTVGQTS(ph)PR_
NF1	Phosphorylation	S2543	0.698	0.655	_S(ph)FDHLISDTK_
PIK3CA	Ubiquitylation	K864	0.390	0.588	_NSHTIM(ox)QIQCK(gl)GGLK_
PIK3CA	Ubiquitylation	K868	0.204	0.651	_NSHTIM(ox)QIQCKGGLK(gl)_
PIK3CA	Ubiquitylation	K974	-0.273		_GAQECTK(gl)TREFER_
RUNX1T1	Ubiquitylation	K489	0.393		_K(gl)AEEAVNEVK_
SMAD3	Ubiquitylation	K13	-0.704		_(ac)SSILPFTPPIVK(gl)R_
WRN	Ubiquitylation	K134		0.717	_MLLENKAVK(gl)_
WRN	Phosphorylation	S1133	0.363	0.023	_SIMVQS(ph)PEK_