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Query: VDAC1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
VDAC1 1 7.191 -1.570 2.490 1.900 -1.029
VDAC1 1 7.191 -1.570 2.490 0.739

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
VDAC1 Ubiquitylation K61 1.135 _VTGSLETK(gl)YR_
VDAC1 Phosphorylation S102 0.928 0.928 _LTFDSS(ph)FSPNTGKK_
VDAC1 Ubiquitylation K20 0.718 0.885 _DVFTK(gl)GYGFGLIK_
VDAC1 Phosphorylation S104 0.569 0.615 _LTFDSSFS(ph)PNTGK_
VDAC1 Phosphorylation T107 0.493 _LTFDSSFSPNT(ph)GKK_
VDAC1 Ubiquitylation K110 0.406 0.270 _LTFDSSFSPNTGKK(gl)_
VDAC1 Ubiquitylation K109 0.352 _LTFDSSFSPNTGK(gl)K_
VDAC1 Ubiquitylation K274 0.839 _NVNAGGHK(gl)LGLGLEFQA_

Background Information for VDAC1:


Pubmed-VDAC1 »
Uniprot-VDAC1 »
Biogrid-VDAC1 »
ProteomicsDB-VDAC1 »

Tumorportal-VDAC1 »
COSMIC-VDAC1 »
GenomeRNAi-VDAC1 »
Genecards-VDAC1


Protein-protein Interactions for VDAC1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AIFM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait FAM82A2 Cat. description Hein, Mann, Cell 2015
Category members IP bait FGFR1OP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait GOLT1B Cat. description Hein, Mann, Cell 2015
Category members IP bait MMGT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MTX2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO19 Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB2A Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB5C Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB7A Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMEM109 Cat. description Hein, Mann, Cell 2015
Category members IP bait VAPA Cat. description Hein, Mann, Cell 2015
Category members IP bait VWA9 Cat. description Hein, Mann, Cell 2015
Category members IP bait VDAC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in VDAC1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Porin_Euk IPR001925 0.72
Category members Porin_Euk/Tom40 IPR027246 0.34


Protein complexes (CORUM database) featuring VDAC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5862 CAV1-VDAC1-ESR1 complex Database 0.11


Categories featuring VDAC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0046930 pore complex Database 1.57
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0042645 mitochondrial nucleoid Database 0.61
Category members GO Category GO:0016020 membrane Database 0.52
Category members Pathway Pathway_32 KEGG_HUNTINGTONS_DISEASE 0 0.46
Category members GO Category GO:0005741 mitochondrial outer membrane Database 0.46
Category members Pathway Pathway_9 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT 0 0.33
Category members GO Category GO:0008308 voltage-gated anion channel activity Database 0.31
Category members GO Category GO:0007268 synaptic transmission Database 0.23
Category members GO Category GO:0005743 mitochondrial inner membrane Database 0.15
Category members Pathway Pathway_233 KEGG_CALCIUM_SIGNALING_PATHWAY 0 0.13
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members GO Category GO:0015288 porin activity Database 0.09
Category members Pathway Pathway_31 KEGG_PARKINSONS_DISEASE 0 0
Category members GO Category GO:0001662 behavioral fear response Database 0
Category members GO Category GO:0006820 anion transport Database 0
Category members GO Category GO:0007270 neuron-neuron synaptic transmission Database 0
Category members GO Category GO:0007612 learning Database 0


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